Anisomycin, an inhibitor of protein synthesis, blocks late phases of LTP phenomena in the hippocampal CA1 region in vitro

@article{Frey1988AnisomycinAI,
  title={Anisomycin, an inhibitor of protein synthesis, blocks late phases of LTP phenomena in the hippocampal CA1 region in vitro},
  author={U. Frey and M. Krug and K. Reymann and H. Matthies},
  journal={Brain Research},
  year={1988},
  volume={452},
  pages={57-65}
}
  • U. Frey, M. Krug, +1 author H. Matthies
  • Published 1988
  • Biology, Medicine
  • Brain Research
  • Long-term potentiation (LTP) with its extremely long duration has been frequently regarded as an elementary mechanism of information storage in the nervous system or at least as a suitable model for the study of mechanisms underlying functional plasticity and processes of learning and memory formation. Considering the necessity of an increased protein synthesis for memory consolidation and for the maintenance of LTP in granular synapses in vivo it was of interest to determine whether the LTP of… CONTINUE READING
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