Amino Acyl-tRNA Synthetases

Known as: RNA Synthetase, Transfer, Amino Acyl tRNA Ligases, Amino Acyl tRNA Synthetases 
A subclass of enzymes that aminoacylate AMINO ACID-SPECIFIC TRANSFER RNA with their corresponding AMINO ACIDS.
National Institutes of Health

Related topics

Related topics

19 relations
Activation of Amino AcidsIn BloodProcess of secretionTransfer RNA Aminoacylation
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Narrower (8)

Asparagine-tRNA ligaseCysteine-tRNA ligaseFAAP protein, mouseGlutamine-tRNA ligase
(More)

Broader (2)

LigaseRNA, Transfer, Amino Acyl

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
A Comprehensive Overview on Myositis-Specific Antibodies: New and Old Biomarkers in Idiopathic Inflammatory Myopathy.
Autoantibodies specific for idiopathic inflammatory myopathy (myositis-specific autoantibodies (MSAs)) are clinically useful… (More)
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2013
2013
Codon usage, amino acid usage, transfer RNA and amino-acyl-tRNA synthetases in Mimiviruses.
Mimiviruses are giant viruses that infect phagocytic protists, including Acanthamoebae spp., which were discovered during the… (More)
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Highly Cited
2012
Highly Cited
2012
Leucyl-tRNA Synthetase Is an Intracellular Leucine Sensor for the mTORC1-Signaling Pathway
Amino acids are required for activation of the mammalian target of rapamycin (mTOR) kinase, which regulates protein translation… (More)
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Highly Cited
2012
Highly Cited
2012
Leucyl-tRNA synthetase controls TORC1 via the EGO complex.
The target of rapamycin complex 1 (TORC1) is an essential regulator of eukaryotic cell growth that responds to growth factors… (More)
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2009
2009
Defining the determinants for dual targeting of amino acyl-tRNA synthetases to mitochondria and chloroplasts.
Most of the organellar amino acyl-tRNA synthetases (aaRSs) are dually targeted to both mitochondria and chloroplasts using dual… (More)
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Highly Cited
2005
Highly Cited
2005
Dual targeting is the rule for organellar aminoacyl-tRNA synthetases in Arabidopsis thaliana.
In plants, protein synthesis occurs in the cytosol, mitochondria, and plastids. Each compartment requires a full set of tRNAs and… (More)
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Highly Cited
1999
Highly Cited
1999
Two distinct cytokines released from a human aminoacyl-tRNA synthetase.
Aminoacyl-tRNA synthetases catalyze aminoacylation of transfer RNAs (tRNAs). It is shown that human tyrosyl-tRNA synthetase can… (More)
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Highly Cited
1999
Highly Cited
1999
Evolution of aminoacyl-tRNA synthetases--analysis of unique domain architectures and phylogenetic trees reveals a complex history of horizontal gene transfer events.
Phylogenetic analysis of aminoacyl-tRNA synthetases (aaRSs) of all 20 specificities from completely sequenced bacterial, archaeal… (More)
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Highly Cited
1995
Highly Cited
1995
The histidyl-tRNA synthetase-related sequence in the eIF-2 alpha protein kinase GCN2 interacts with tRNA and is required for activation in response to starvation for different amino acids.
Protein kinase GCN2 is a multidomain protein that contains a region homologous to histidyl-tRNA synthetases juxtaposed to the… (More)
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Review
1990
Review
1990
Polymyositis, pulmonary fibrosis and autoantibodies to aminoacyl-tRNA synthetase enzymes.
The clinical and laboratory features of 29 patients who had one of three anti-aminoacyl-tRNA synthetase autoantibodies, anti-Jo1… (More)
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