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Amiloride

Known as: 3,5-Diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide, Amiloride [Chemical/Ingredient], Amiloridum 
A synthetic pyrazine derivative with antikaliuretic and diuretic properties. Amiloride inhibits sodium channels located in the distal tubules and… 
National Institutes of Health

Related topics

Related topics

43 relations

Narrower (21)

2',4'-dichlorobenzamil amiloride2',4'-dimethylbenzamil2'-methoxy-5'-nitrobenzamil3',4'-dichlorobenzamil

Broader (4)

Acid Sensing Ion Channel BlockersDiureticsEpithelial Sodium Channel BlockersPyrazinamide
Amiloride HydrochlorideAnuriaCystic FibrosisDecreased Renal Ca++ Excretion [PE]

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1994
Highly Cited
1994
Evidence that Na+/H+ exchanger isoforms NHE1 and NHE3 exist as stable dimers in membranes with a high degree of specificity for homodimers.
Highly Cited
1993
Highly Cited
1993
Functional properties of the rat Na/H exchanger NHE-2 isoform expressed in Na/H exchanger-deficient Chinese hamster ovary cells.
Highly Cited
1991
Highly Cited
1991
Alpha-thrombin, epidermal growth factor, and okadaic acid activate the Na+/H+ exchanger, NHE-1, by phosphorylating a set of common sites.
Highly Cited
1991
Highly Cited
1991
Inhibition of Na+/Ca2+ exchange enhances delayed neuronal death elicited by glutamate in cerebellar granule cell cultures
Highly Cited
1991
Highly Cited
1991
Amiloride-sensitive sodium channel is linked to the cytoskeleton in renal epithelial cells.
Amiloride-sensitive sodium channels are localized to the microvillar domain of apical membranes in sodium-transporting renal… 
Highly Cited
1985
Highly Cited
1985
Role of a Na+-dependent Cl-/HCO3- exchange in regulation of intracellular pH in fibroblasts.
Highly Cited
1983
Highly Cited
1983
Activation of Na+/H+ exchange by epidermal growth factor elevates intracellular pH in A431 cells.
Highly Cited
1983
Highly Cited
1983
Interaction of external H+ with the Na+-H+ exchanger in renal microvillus membrane vesicles.
Highly Cited
1982
Highly Cited
1982
Evidence that a Na+/Ca2+ antiport system regulates murine erythroleukemia cell differentiation.
Highly Cited
1979
Highly Cited
1979
Increased sodium ion influx is necessary to initiate rat hepatocyte proliferation
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