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Amiloride

Known as: 3,5-Diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide, Amiloride [Chemical/Ingredient], Amiloridum 
A synthetic pyrazine derivative with antikaliuretic and diuretic properties. Amiloride inhibits sodium channels located in the distal tubules and… 
National Institutes of Health

Related topics

Related topics

43 relations

Narrower (21)

2',4'-dichlorobenzamil amiloride2',4'-dimethylbenzamil2'-methoxy-5'-nitrobenzamil3',4'-dichlorobenzamil

Broader (4)

Acid Sensing Ion Channel BlockersDiureticsEpithelial Sodium Channel BlockersPyrazinamide
Amiloride HydrochlorideAnuriaCystic FibrosisDecreased Renal Ca++ Excretion [PE]

Papers overview

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2005
2005
Amiloride-sensitive Na+ transport in human red cells: Evidence for a Na/H exchange system
SummaryThe role of transmembrane pH gradients on the ouabain, bumetanide and phloretin-resistant Na+ transport was studied in… 
2002
2002
Alveolar epithelial ion and fluid transport: β-adrenergic regulation of amiloride-sensitive lung sodium channels
We investigated the mechanism by which cAMP increases sodium transport in lung epithelial cells. Alveolar type II (ATII) cells… 
1997
1997
Direct determination of amiloride in urine using isopotential fluorimetry.
A method for the determination of amiloride at concentrations between 15 and 152 ng ml - 1 by means of matrix… 
1994
1994
Endotoxin-stimulated alveolar macrophages impair lung epithelial Na+ transport by an L-Arg-dependent mechanism.
The Na+ transport function of alveolar epithelium represents an important mechanism for air space fluid clearance after acute… 
1987
1987
The control of mediator release from RBL-2H3 cells: roles for Ca2+, Na+, and protein kinase C1.
Antigen-stimulated rat basophilic leukemia (RBL-2H3) cells release serotonin and other inflammatory mediators by a process that… 
1986
1986
Amiloride inhibition of DNA synthesis and immunoglobulin production by activated human peripheral blood mononuclear cells is independent of sodium/hydrogen antiport.
Activation of sodium/proton (Na+/H+) antiport activity has been shown to occur as an early event in mitogenesis. Because… 
1986
1986
Amiloride added together with bumetanide completely blocks mouse 3T3-cell exit from G0/G1-phase and entry into S-phase.
In this study we tested the hypothesis that stimulation of univalent-cation fluxes which follow the addition of growth factors… 
1985
1985
Differentiation of the active sodium transport system during metamorphosis in Rana catesbeiana skin in relation to cadmium- and amiloride-induced responses.
The differentiation of the sodium active transport system across Rana catesbeiana skin during metamorphosis was investigated and… 
1984
1984
Amiloride and diltiazem inhibition of microsomal and mitochondrial Na+ and Ca2+ transport.
Amiloride, a K+-sparing diuretic, and diltiazem, a Ca2+ channel antagonist, have both been reported to inhibit Na+ transport… 
1981
1981
Cardiac Effects of Amiloride in the Dog
Summary The cardiac effects of amiloride, a potassium-sparing diuretic, were investigated in isolated, blood-perfused…