Skip to search formSkip to main contentSkip to account menu

Pyrazinamide

Known as: Pyrazineamide, Pyrazinamide [Chemical/Ingredient], Pirazinamida 
A synthetic pyrazinoic acid amide derivative with bactericidal property. Pyrazinamide is particularly active against slowly multiplying intracellular… 
National Institutes of Health

Related topics

Related topics

36 relations

Narrower (13)

4-acetoxybenzyl pyrazinoate5-chloropyrazinamide5-chloropyrazinoic acid5-hydroxypyrazinamide
Antimycobacterial agentGoutHypersensitivityIn Blood

Broader (2)

Antitubercular Agentspyrazine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Mycobacterium tuberculosis Pyrazinamide Resistance Determinants: a Multicenter Study
ABSTRACT Pyrazinamide (PZA) is a prodrug that is converted to pyrazinoic acid by the enzyme pyrazinamidase, encoded by the pncA… 
Highly Cited
2012
Highly Cited
2012
Host cell autophagy activated by antibiotics is required for their effective antimycobacterial drug action.
Highly Cited
2010
Highly Cited
2010
Role of aspirin in tuberculous meningitis: A randomized open label placebo controlled trial
Highly Cited
2006
Highly Cited
2006
Determinants of Rifampin, Isoniazid, Pyrazinamide, and Ethambutol Pharmacokinetics in a Cohort of Tuberculosis Patients
ABSTRACT Evaluation of sources of pharmacokinetic variation can facilitate optimization of tuberculosis treatment regimens by… 
Highly Cited
2006
Highly Cited
2006
Aspirin and ibuprofen enhance pyrazinamide treatment of murine tuberculosis.
OBJECTIVES Aspirin (acetylsalicylic acid) or ibuprofen [2-(4-isobutyl-phenyl)-propionic acid] was administered to mice undergoing… 
Highly Cited
2005
Highly Cited
2005
Inhalable alginate nanoparticles as antitubercular drug carriers against experimental tuberculosis.
Highly Cited
2005
Highly Cited
2005
Solid lipid particle-based inhalable sustained drug delivery system against experimental tuberculosis.
Highly Cited
2005
Highly Cited
2005
Oral solid lipid nanoparticle-based antitubercular chemotherapy.
Review
1998
Review
1998
Regulation of renal urate excretion: a critical review.
Review
1994
Review
1994
Mechanisms of drug resistance in Mycobacterium tuberculosis.
Reference EPFL-REVIEW-151418View record in PubMed Record created on 2010-09-07, modified on 2017-05-12 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)