Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Pyrazinamide

Known as: Pyrazineamide, Pyrazinamide [Chemical/Ingredient], Pirazinamida 
A synthetic pyrazinoic acid amide derivative with bactericidal property. Pyrazinamide is particularly active against slowly multiplying intracellular… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Outbreaks of Ebola hemorrhagic fever in sub-Saharan Africa are associated with case fatality rates of up to 90%. Currently… Expand
Is this relevant?
Review
2013
Review
2013
Despite the introduction 40 years ago of the inexpensive and effective four-drug (isoniazid, rifampicin, pyrazinamide and… Expand
  • table 1
  • figure 1
  • figure 2
  • table 2
  • table 2
Is this relevant?
Highly Cited
2012
Highly Cited
2012
BACKGROUND New drugs, but also shorter, better-tolerated regimens are needed to tackle the high global burden of tuberculosis… Expand
  • table 1
  • table 2
  • table 3
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2009
Highly Cited
2009
BACKGROUND The study documented the emergence of new forms of resistant bacilli (totally drug-resistant [TDR] or super… Expand
  • table 1
  • table 2
Is this relevant?
Highly Cited
2006
Highly Cited
2006
ABSTRACT Evaluation of sources of pharmacokinetic variation can facilitate optimization of tuberculosis treatment regimens by… Expand
  • table 1
  • table 2
  • figure 1
  • table 3
  • figure 2
Is this relevant?
Highly Cited
2005
Highly Cited
2005
The incidence of tuberculosis has been increasing substantially on a worldwide basis over the past decade, but no tuberculosis… Expand
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Pyrazinamide is an important sterilizing drug that shortens tuberculosis (TB) therapy. However, the mechanism of action of… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Review
2001
Review
2001
Multidrug-resistant (MDR) strains of Mycobacterium tuberculosis have emerged worldwide. In many countries and regions, these… Expand
  • figure 1
Is this relevant?
Highly Cited
1996
Highly Cited
1996
The aim of this study was to determine the current incidence of side-effects severe enough to cause intolerance of standard… Expand
Is this relevant?
Highly Cited
1967
Highly Cited
1967
Pyrazinamide, an analogue of nicotinamide, has the unique property of sterilizing large populations of M. tuberculosis with… Expand
Is this relevant?