Affinity Reagent

In chemistry and biology, a compound that binds specific substances, such as proteins or nucleic acids. Many affinity reagents are antibodies. They… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2018
05101519762018

Papers overview

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Highly Cited
2014
Highly Cited
2014
Broadly neutralizing antibodies (bnAbs) targeting the trimer apex of HIV envelope are favored candidates for vaccine design and… (More)
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2010
2010
volume 28 number 7 july 2010 nature biotechnology With the broadening availability of tools and methods, researchers have to… (More)
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2009
2009
Antibodies are widely used for diagnostic and therapeutic applications because of their sensitive and specific recognition of a… (More)
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2003
2003
We have applied in vivo intracellular antibody capture (IAC) technology to isolate human intrabodies which bind to the oncogenic… (More)
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Highly Cited
2002
Highly Cited
2002
To identify human proteins that bind to the Smac and caspase-9 binding pocket on the baculoviral inhibitor of apoptosis protein… (More)
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Highly Cited
2002
Highly Cited
2002
The granule exocytosis cytotoxicity pathway is the major molecular mechanism for cytotoxic T lymphocyte (CTL) and natural killer… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Biologically active natural products continue to be useful in the exploration and control of intracellular signaling… (More)
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2001
2001
Phosphatidic acid (PA) is an important bioactive lipid, but its molecular targets remain unknown. To identify such targets, we… (More)
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Highly Cited
1999
Highly Cited
1999
The Drosophila gene groucho (gro) encodes a transcriptional corepressor that has critical roles in many development processes. In… (More)
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1984
1984
Nicotinic acetylcholine receptors contain a readily reducible disulfide bond at the periphery of the acetylcholine binding site… (More)
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