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ARHGEF7 gene

Known as: BETA-PIX, PIXB, DKFZp686C12170 
This gene plays a role in apoptosis and GTPase-mediated signaling.
National Institutes of Health

Related topics

Related topics

6 relations
ARHGEF15 genePositive Regulation of ApoptosisRho Guanine Nucleotide Exchange Factor 7, humanRho guanine nucleotide exchange factor 7

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ARHGEF7 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
NFκB1 (p50) suppresses SOD2 expression by inhibiting FoxO3a transactivation in a miR190/PHLPP1/Akt-dependent axis
This study reports a novel function of p50 in its regulation of SOD2 transcription via an NFκB-independent pathway. p50-regulated… 
2013
2013
Association study of polymorphisms in the alpha 7 nicotinic acetylcholine receptor subunit and catechol-o-methyl transferase genes with sensory gating in first-episode schizophrenia
2002
2002
Positive and Negative Effects of the Major Mammalian Messenger Ribonucleoprotein p50 on Binding of 40 S Ribosomal Subunits to the Initiation Codon of β-Globin mRNA*
p50, the major core protein bound to mammalian mRNAs, has been reported to stimulate translation at low p50/mRNA ratios and… 
Highly Cited
2002
Highly Cited
2002
NFkappaB1 (p50)-deficient mice are not susceptible to multiple low-dose streptozotocin-induced diabetes.
Insulin-dependent diabetes mellitus (IDDM) is a disease characterized by the autoimmune destruction of the pancreatic beta-cells… 
Review
1999
Review
1999
Translational regulation by Y-box transcription factor: involvement of the major mRNA-associated protein, p50.
Highly Cited
1998
Highly Cited
1998
Chronic Inflammation and Susceptibility to Bacterial Infections in Mice Lacking the Polypeptide (p)105 Precursor (NF-κB1) but Expressing p50
The polypeptide (p)50 molecule, a subunit of nuclear factor (NF)-κB, is produced after proteolytic processing of the p105… 
Highly Cited
1997
Highly Cited
1997
Overexpression in COS cells of p50, the major core protein associated with mRNA, results in translation inhibition.
p50, the major core protein of messenger ribonucleoprotein particles (mRNPs) in the cytoplasm of somatic mammalian cells, has… 
Highly Cited
1996
Highly Cited
1996
Developmental and genetic influences on the p50 sensory gating phenotype
Highly Cited
1993
Highly Cited
1993
Promoter of the human NF-kappa B p50/p105 gene. Regulation by NF-kappa B subunits and by c-REL.
NF-kappa B is a transcription factor involved in the regulation of numerous genes encoding proteins involved in immune function… 
Highly Cited
1993
Highly Cited
1993
HTLV-I encoded Tax in association with NF-kappa B precursor p105 enhances nuclear localization of NF-kappa B p50 and p65 in transfected cells.
NF-kappa B is a heterodimeric protein composed of two subunits, p50 and p65, and is sequestered in the cytoplasm as an inactive… 
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