Skip to search formSkip to main contentSkip to account menu

ABCB1 wt Allele

Known as: ABC20, GP170, P-Glycoprotein Transporter C Allele 
Human ABCB1 wild-type allele is located in the vicinity of 7q21.1 and is approximately 210 kb in length. This allele, which encodes multidrug… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Quinazolinones, indolo‐ and pyrrolopyrimidines with inhibitory effects toward ABCB1 (P‐gp) and ABCC1 (MRP1) transporters were… 
2007
2007
Background Several studies have evaluated the role of the multidrug resistance 1 gene (MDR1) polymorphism, which encodes the… 
Highly Cited
2006
Highly Cited
2006
1 Breast cancer resistance protein (BCRP, ABCG2) is a drug efflux transporter that is believed to affect the drug disposition of… 
Highly Cited
2005
Highly Cited
2005
The placenta plays an important role in modulating xenobiotic passage from mother to fetus. Studies in mice have demonstrated… 
Review
2003
Review
2003
Long term treatment with antiepileptic drugs (AEDs) is the standard therapeutic approach to eradicate seizures. However, a small… 
Highly Cited
1998
Highly Cited
1998
The human multidrug transporter (MDR1 or P-glycoprotein) is an ATP-dependent cellular drug extrusion pump, and its function… 
Highly Cited
1994
Highly Cited
1994
BACKGROUND Overexpression of P-glycoprotein has been associated with a worse prognosis for some groups of patients not receiving… 
Highly Cited
1987
Highly Cited
1987
SummaryMultiple drug resistance has been shown to be associated with amplification/increased expression of a gene designated MDR…