ABCB1 wt Allele

Known as: ABC20, GP170, P-Glycoprotein Transporter C Allele 
Human ABCB1 wild-type allele is located in the vicinity of 7q21.1 and is approximately 210 kb in length. This allele, which encodes multidrug… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2017
05010019732017

Related topics

Related topics

13 relations
7q21.1ABCB1 protein, humanCrohn DiseaseDrug Efflux
(More)

Broader (1)

ABCB1 gene

Related mentions per year

Related mentions per year

1936-2019
19401960198020002020
ABCB1 wt Allele
Crohn Disease
Multi-Drug Resistance
Ligand Binding
Transmembrane Transport
Homo sapiens

Papers overview

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Highly Cited
2010
Highly Cited
2010
A variational theory of hyperbolic Lagrangian Coherent Structures
We develop a mathematical theory that clarifies the relationship between observable Lagrangian Coherent Structures (LCSs) and… (More)
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Highly Cited
2008
Highly Cited
2008
Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin.
Many chemotherapy regiments are successfully used to treat breast cancer; however, often breast cancer cells develop drug… (More)
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Highly Cited
2005
Highly Cited
2005
Chronic imatinib mesylate exposure leads to reduced intracellular drug accumulation by induction of the ABCG2 (BCRP) and ABCB1 (MDR1) drug transport pumps.
Imatinib mesylate is a selective tyrosine kinase inhibitor that is successfully used in the treatment of Philadelphia-positive… (More)
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Highly Cited
2001
Highly Cited
2001
Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin.
Intestinal P-glycoprotein, which is encoded by the MDR1 gene, plays an important role in the absorption and presystemic… (More)
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Highly Cited
2001
Highly Cited
2001
Detection of Multiple Gene Amplifications in Glioblastoma Multiforme Using Array-Based Comparative Genomic Hybridization
We have used a new method of genomic microarray to investigate amplification of oncogenes throughout the genome of glioblastoma… (More)
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Highly Cited
1998
Highly Cited
1998
Development of a model for training and evaluation of laparoscopic skills.
BACKGROUND Interest in the training and evaluation of laparoscopic skills is extending beyond the realm of the operating room to… (More)
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Highly Cited
1998
Highly Cited
1998
Direct involvement of the Y-box binding protein YB-1 in genotoxic stress-induced activation of the human multidrug resistance 1 gene.
The human multidrug resistance 1 (MDR1) gene encoding P-glycoprotein is often overexpressed in various human tumors after… (More)
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Highly Cited
1996
Highly Cited
1996
P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans.
The P-glycoprotein (Pgp) efflux pump can influence the hepatocellular concentration of xenobiotics that are modulators and… (More)
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Highly Cited
1992
Highly Cited
1992
Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1.
Experiments were performed to determine if retroviral-mediated transfer of the human multidrug resistance 1 gene (MDR1) into… (More)
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Highly Cited
1992
Highly Cited
1992
Modulation of multidrug-resistant multiple myeloma by cyclosporin. The Leukaemia Group of the EORTC and the HOVON.
Resistance to chemotherapy in refractory multiple myeloma is frequently associated with expression of multidrug resistance (MDR… (More)
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