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Crohn Disease

Known as: Crohn's disease NOS, disease crohn, eleocolitis 
A condition in which the gastrointestinal tract is inflamed over a long period of time. Regional enteritis usually affects the small intestine and… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND The comparative efficacy and safety of infliximab and azathioprine therapy alone or in combination for Crohn's disease… Expand
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Highly Cited
2010
Highly Cited
2010
We undertook a meta-analysis of six Crohn's disease genome-wide association studies (GWAS) comprising 6,333 affected individuals… Expand
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Highly Cited
2008
Highly Cited
2008
Several risk factors for Crohn's disease have been identified in recent genome-wide association studies. To advance gene… Expand
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Highly Cited
2008
Highly Cited
2008
A decrease in the abundance and biodiversity of intestinal bacteria within the dominant phylum Firmicutes has been observed… Expand
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Infliximab, a monoclonal antibody against tumor necrosis factor, is an effective maintenance therapy for patients with… Expand
Highly Cited
2002
Highly Cited
2002
BACKGROUND We did a randomised controlled trial to assess the benefit of maintenance infliximab therapy in patients with active… Expand
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Highly Cited
2001
Highly Cited
2001
Crohn's disease and ulcerative colitis, the two main types of chronic inflammatory bowel disease, are multifactorial conditions… Expand
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Highly Cited
2001
Highly Cited
2001
Crohn's disease is a chronic inflammatory disorder of the gastrointestinal tract, which is thought to result from the effect of… Expand
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Highly Cited
1997
Highly Cited
1997
Background Studies in animals and an open-label trial have suggested a role for antibodies to tumor necrosis factor… Expand
Highly Cited
1976
Highly Cited
1976
Needing a single index of degree of illness in Crohn's disease, the National Cooperative Crohn's Disease Study group collected… Expand