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Crohn Disease

Known as: Crohn's disease NOS, disease crohn, eleocolitis 
A condition in which the gastrointestinal tract is inflamed over a long period of time. Regional enteritis usually affects the small intestine and… Expand
National Institutes of Health

Related topics

Related topics

48 relations
ABCB1 geneABCB1 wt AlleleAdenocarcinoma of the small intestineAphthous Stomatitis
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Broader (5)

ColitisDisease as reason for lower g.i. examinationInflammatory Bowel Diseasesautoimmune inflammatory bowel disease
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Narrower (2)

Crohn's disease of the ileumIIeocolitis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Infliximab, azathioprine, or combination therapy for Crohn's disease.
BACKGROUND The comparative efficacy and safety of infliximab and azathioprine therapy alone or in combination for Crohn's disease… Expand
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Highly Cited
2010
Highly Cited
2010
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
We undertook a meta-analysis of six Crohn's disease genome-wide association studies (GWAS) comprising 6,333 affected individuals… Expand
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Highly Cited
2008
Highly Cited
2008
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
Several risk factors for Crohn's disease have been identified in recent genome-wide association studies. To advance gene… Expand
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Highly Cited
2008
Highly Cited
2008
Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
A decrease in the abundance and biodiversity of intestinal bacteria within the dominant phylum Firmicutes has been observed… Expand
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Highly Cited
2004
Highly Cited
2004
Infliximab maintenance therapy for fistulizing Crohn's disease.
BACKGROUND Infliximab, a monoclonal antibody against tumor necrosis factor, is an effective maintenance therapy for patients with… Expand
Highly Cited
2002
Highly Cited
2002
Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial
BACKGROUND We did a randomised controlled trial to assess the benefit of maintenance infliximab therapy in patients with active… Expand
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Highly Cited
2001
Highly Cited
2001
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
Crohn's disease and ulcerative colitis, the two main types of chronic inflammatory bowel disease, are multifactorial conditions… Expand
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Highly Cited
2001
Highly Cited
2001
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
Crohn's disease is a chronic inflammatory disorder of the gastrointestinal tract, which is thought to result from the effect of… Expand
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Highly Cited
1997
Highly Cited
1997
A Short-Term Study of Chimeric Monoclonal Antibody cA2 to Tumor Necrosis Factor α for Crohn's Disease
Background Studies in animals and an open-label trial have suggested a role for antibodies to tumor necrosis factor… Expand
Highly Cited
1976
Highly Cited
1976
Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study.
Needing a single index of degree of illness in Crohn's disease, the National Cooperative Crohn's Disease Study group collected… Expand
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