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The comparative efficacy and safety of infliximab and azathioprine therapy alone or in combination for Crohn's disease… Expand We undertook a meta-analysis of six Crohn's disease genome-wide association studies (GWAS) comprising 6,333 affected individuals… Expand Several risk factors for Crohn's disease have been identified in recent genome-wide association studies. To advance gene… Expand A decrease in the abundance and biodiversity of intestinal bacteria within the dominant phylum Firmicutes has been observed… Expand BACKGROUND
Infliximab, a monoclonal antibody against tumor necrosis factor, is an effective maintenance therapy for patients with… Expand BACKGROUND
We did a randomised controlled trial to assess the benefit of maintenance infliximab therapy in patients with active… Expand Crohn's disease and ulcerative colitis, the two main types of chronic inflammatory bowel disease, are multifactorial conditions… Expand Crohn's disease is a chronic inflammatory disorder of the gastrointestinal tract, which is thought to result from the effect of… Expand Background Studies in animals and an open-label trial have suggested a role for antibodies to tumor necrosis factor… Expand Needing a single index of degree of illness in Crohn's disease, the National Cooperative Crohn's Disease Study group collected… Expand