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National Institutes of Health
analogs & derivatives
Semantic Scholar uses AI to extract papers important to this topic.
The biochemical and pharmacological activity of 9-benzyl-9-deazaguanine, a potent purine nucleoside phosphorylase (PNP) inhibitor
Corpus ID: 6027060
Patients deficient in purine nucleoside phosphorylase (PNP), show marked impairment in T-cell immune function but normal to…
Effect of 9-benzyl-9-deazaguanine, a potent inhibitor of purine nucleoside phosphorylase, on the cytotoxicity and metabolism of 6-thio-2'-deoxyguanosine.
L. L. Bennett
Corpus ID: 5798968
6-Thio-2'-deoxyguanosine (T-dGuo) has been reported to be both phosphorylated by deoxycytidine kinase and converted to 6…
Purine nucleoside phosphorylase inhibitors: biochemical and pharmacological studies with 9-benzyl-9-deazaguanine and related compounds.
L. L. Bennett
The Journal of pharmacology and experimental…
Corpus ID: 2064591
Certain derivatives of 9-deazaguanine that contain arylmethyl, heteroarylmethyl or cycloalkylmethyl groups at the 9-position are…
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