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6-chrysenamine
Known as:
6-chrysylamine
, 6-chrysenylamine
, chrysenex
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National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Antineoplastic Agents
Chrysenes
Narrower (1)
CP 1001
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1993
1993
Roles of human hepatic and pulmonary cytochrome P450 enzymes in the metabolism of the environmental carcinogen 6-nitrochrysene.
Young-Heum Chae
,
C. Yun
,
F. Guengerich
,
F. Kadlubar
,
K. El-Bayoumy
Cancer Research
1993
Corpus ID: 17863398
6-Nitrochrysene is remarkably tumorigenic in the lung and liver of newborn mice and approximates the activities of certain…
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1989
1989
Mutagenicity, metabolism and DNA adduct formation of 6-nitrochrysene in Salmonella typhimurium.
K. El-Bayoumy
,
K. Delclos
,
R. Heflich
,
R. Walker
,
G. Shiue
,
S. Hecht
Mutagenesis
1989
Corpus ID: 19943698
The mutagenic activities of 6-nitrochrysene (6-NC) and its previously identified metabolites were evaluated in Salmonella…
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1989
1989
Comparative tumorigenicity of 6-nitrochrysene and its metabolites in newborn mice.
K. El-Bayoumy
,
G. Shiue
,
S. Hecht
Carcinogenesis
1989
Corpus ID: 32580586
The tumorigenic activities of 6-nitrochrysene and its metabolites were evaluated in the newborn mouse model. Groups of mice were…
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1988
1988
Metabolism of the carcinogen [3H]6-nitrochrysene in the preweanling mouse: identification of 6-aminochrysene-1,2-dihydrodiol as the probable proximate carcinogenic metabolite.
K. Delclos
,
Karan EI- Bayoumy
,
S. Hecht
,
R. Walker
,
F. Kadlubar
Carcinogenesis
1988
Corpus ID: 24476382
6-Nitrochrysene (NC) is a potent lung and liver carcinogen when administered in multiple doses to preweanling mice. We have…
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1988
1988
Metabolism of 6-nitrochrysene by intestinal microflora
B. W. Manning
,
W. Campbell
,
W. Franklin
,
K. Delclos
,
C. Cerniglia
Applied and Environmental Microbiology
1988
Corpus ID: 2771220
Since bacterial nitroreduction may play a critical role in the activation of nitropolycyclic aromatic hydrocarbons, we have used…
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1987
1987
Identification of C8-modified deoxyinosine and N2- and C8-modified deoxyguanosine as major products of the in vitro reaction of N-hydroxy-6-aminochrysene with DNA and the formation of these adducts…
K. Delclos
,
D. W. Miller
,
+4 authors
F. Kadlubar
Carcinogenesis
1987
Corpus ID: 40086055
Since 6-nitrochrysene and 6-aminochrysene have shown activity in carcinogenicity bioassays, we have begun an investigation of…
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1987
1987
Carcinogen-DNA adduct formation in the lungs and livers of preweanling CD-1 male mice following administration of [3H]-6-nitrochrysene, [3H]-6-aminochrysene, and [3H]-1,6-dinitropyrene.
Delclos Kb
,
R. Walker
,
Dooley Kl
,
P. Fu
,
F. Kadlubar
Cancer Research
1987
Corpus ID: 20748368
6-Nitrochrysene (NC) and 6-aminochrysene (AC) have been shown to be potent lung and liver carcinogens when administered in…
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1984
1984
Identification of trans-1,2-dihydro-1,2-dihydroxy-6-nitrochrysene as a major mutagenic metabolite of 6-nitrochrysene.
K. El-Bayoumy
,
S. Hecht
Cancer Research
1984
Corpus ID: 20807492
Liver 9000 X g supernatant from rats was used to study the metabolism of [6- 14C]nitrochrysene under aerobic conditions. The…
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Highly Cited
1975
Highly Cited
1975
Mutagenesis of certain activated carcinogens in vitro associated with genetically mediated increases in monooxygenase activity and cytochrome P 1-450.
J. Felton
,
D. W. Nebert
Journal of Biological Chemistry
1975
Corpus ID: 25538288
1969
1969
Induction of Liver and Lung Tumours in Mice by 6-Aminochrysene administered during the First 3 Days of Life
F. Roe
,
R. Carter
,
S. Adamthwaite
Nature
1969
Corpus ID: 4246055
IN 1953, Rudali and his colleagues1 reported the effects of 6-aminochrysene (Fig. 1) in mice and showed that this substance…
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