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5,8,11,14-Eicosatetraynoic Acid

Known as: 5,8,11,14 Eicosatetraynoic Acid, 5,8,11,14-Eicosatetraynoic Acid [Chemical/Ingredient], ETYA 
A 20-carbon unsaturated fatty acid containing 4 alkyne bonds. It inhibits the enzymatic conversion of arachidonic acid to prostaglandins E(2) and F… 
National Institutes of Health

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11 relations

Narrower (3)

4,7,10,13-eicosatetraynoic acid5,8,11,14-heneicosatetraynoic acidTriarachidonin
In BloodProcess of secretionagonistsanalogs & derivatives

Papers overview

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Highly Cited
2000
Highly Cited
2000
Up-Regulation of Peroxisome Proliferator-Activated Receptors (PPAR-α) and PPAR-γ Messenger Ribonucleic Acid Expression in the Liver in Murine Obesity: Troglitazone Induces Expression of PPAR…
Peroxisome proliferator-activated receptors (PPARs) are transcription factors that play an important role in the regulation of… 
Highly Cited
1998
Highly Cited
1998
Identification of high-affinity binding sites for the insulin sensitizer rosiglitazone (BRL-49653) in rodent and human adipocytes using a radioiodinated ligand for peroxisomal proliferator-activated…
A radioiodinated ligand, [125I]SB-236636 [(S)-(-)3-[4-[2-[N-(2-benzoxazolyl)-N-methylamino]ethoxy]3-[125I]i odo phenyl]2-ethoxy… 
Highly Cited
1993
Highly Cited
1993
Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers.
The nuclear hormone receptors called PPARs (peroxisome proliferator-activated receptors alpha, beta, and gamma) regulate the… 
Review
1993
Review
1993
Positive regulation of the peroxisomal β‐oxidation pathway by fatty acids through activation of peroxisome proliferator‐activated receptors (PPAR)
Highly Cited
1992
Highly Cited
1992
Arachidonic acid inhibits myosin light chain phosphatase and sensitizes smooth muscle to calcium.
Highly Cited
1984
Highly Cited
1984
Comparative effects of indomethacin, acetylenic acids, 15-HETE, nordihydroguaiaretic acid and BW755C on the metabolism of arachidonic acid in human leukocytes and platelets.
Highly Cited
1984
Highly Cited
1984
The influence of lipoxygenase inhibitors on the in vitro production of human leukocytic pyrogen and lymphocyte activating factor (interleukin-1).
Highly Cited
1984
Highly Cited
1984
Effects of non-steroidal anti-inflammatory agents on human neutrophil functions in vitro and in vivo.
Highly Cited
1983
Highly Cited
1983
Role of the endothelium in the vasodilator response of rat thoracic aorta to histamine.
Highly Cited
1974
Highly Cited
1974
Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets.
Arachidonic acid incubated with human platelets was converted into three compounds, 12L-hydroxy-5,8,10,14-eicosatetraenoic acid… 
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