Skip to search formSkip to main contentSkip to account menu

3-N-(2-fluoroethyl)spiperone

Known as: 3-(2'-fluoroethyl)spiperone, FESP 
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (1)

18F-FESP

Broader (2)

RadiopharmaceuticalsSpiperone
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Positron Emission Tomography Displacement Sensitivity: Predicting Binding Potential Change for Positron Emission Tomography Tracers Based on Their Kinetic Characteristics
There is great interest in positron emission tomography (PET) as a noninvasive assay of fluctuations in synaptic neurotransmitter… 
Highly Cited
2006
Highly Cited
2006
Determinants of Route Choice and Value of Traveler Information
Drivers receive value from traveler information in several ways, including the ability to save time, but perhaps more important… 
Highly Cited
2004
Highly Cited
2004
Single-Walled Carbon Nanotube AFM Probes: Optimal Imaging Resolution of Nanoclusters and Biomolecules in Ambient and Fluid Environments
Carbon nanotubes are potentially ideal atomic force microscopy (AFM) probes due to their well-defined geometry, robust mechanical… 
2004
2004
Cerebral D2 and 5-HT2 Receptor occupancy in Schizophrenic Patients Treated with Olanzapine Or Clozapine
We report the results of a double-blind, randomized prospective trial on D2 and 5-HT2 receptor occupancy and the clinical effects… 
Highly Cited
2001
Highly Cited
2001
Noninvasive, quantitative imaging in living animals of a mutant dopamine D2 receptor reporter gene in which ligand binding is uncoupled from signal transduction
The dopamine D2 receptor (D2R) has been used in adenoviral delivery systems and in tumor cell xenografts as an in vivo reporter… 
Highly Cited
1999
Highly Cited
1999
Repetitive, non-invasive imaging of the dopamine D2 receptor as a reporter gene in living animals
Reporter genes (eg β-galactosidase, chloramphenicol-acetyltransferase, green fluorescent protein, luciferase) play critical roles… 
1990
1990
3-(2'-[18F]fluoroethyl)spiperone, a potent dopamine antagonist: synthesis, structural analysis and in-vivo utilization in humans.
1990
1990
In vitro Pharmacological Profile of 3-N-(2-Fluoroethyl)Spiperone
The binding affinities of spiperone and 3-N-(2-fluoroethyl)spiperone (FESP) have been compared for several rodent brain receptor… 
Highly Cited
1989
Highly Cited
1989
3-(2'-[18F]Fluoroethyl)Spiperone: In vivo Biochemical and Kinetic Characterization in Rodents, Nonhuman Primates, and Humans
3-(2'-[18F]fluoroethyl)spiperone (FESP), a recently developed dopamine D2-receptor binding radiopharmaceutical, was used for… 
1989
1989
Models for in vivo Kinetic Interactions of Dopamine D2-Neuroreceptors and 3-(2'-[18F]Fluoroethyl)Spiperone Examined with Positron Emission Tomography
The in vivo tracer kinetics of 3-(2apos;-[18F]fluoroethyl)spiperone (FESP) in the caudate/striatum and cerebellar regions of the… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)