Spiperone

Known as: Spiroperidol, Spiperone [Chemical/Ingredient], 1,3,8-Triazaspiro(4.5)decan-4-one, 8-(4-(4-fluorophenyl)-4-oxobutyl)-1-phenyl- 
A spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1965-2017
051019652017

Papers overview

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2008
2008
Glial activation and neuroinflammatory processes play an important role in the pathogenesis of neurodegenerative diseases such as… (More)
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1995
1995
When injected unilaterally into the mouse striatum, cannabinoid agonists such as Win 55212-2 (1-100 ng/mouse), CP 55940 (0.1-50… (More)
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1988
1988
We measured the inhibition of forskolin-stimulated adenylate cyclase by 5-hydroxytryptamine (5-HT) and other serotonin agonists… (More)
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Highly Cited
1987
Highly Cited
1987
1. The actions of serotonin (5-HT) on pyramidal cells of the CA1 region of the rat hippocampus were characterized using… (More)
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1985
1985
The predominant effect of bath perfusion of 5-HT on CA1 population spikes in rat dorsal hippocampal slices in vitro is a dose… (More)
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1985
1985
The pharmacologic properties of phencyclidine were assessed in adult, male rats using a three-chambered, place-conditioning… (More)
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1977
1977
3H-Spiroperidol of high specific radioactivity labels dopamine receptors in membranes of bovine caudate nucleus and anterior… (More)
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1975
1975
1. The effects of dopamine on the sensory discharges originating from arterial chemo- and baroreceptors were studied in vitro… (More)
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1974
1974
Spiroperidol, which blocks dopamine (DA) receptors, attenuated self-stimulation of the nucleus accumbens, septal area… (More)
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