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- Publications
- Influence
TOMOGRAPHIC MEASUREMENT OF LOCAL CEREBRAL GLUCOSE METABOLIC RATE IN HUMANS WITH (F‐18)2‐FLUORO-2‐DEOXY-D‐GLUCOSE: VALIDATION OF METHOD
- M. Phelps, S. Huang, E. Hoffman, C. Selin, L. Sokoloff, D. Kuhl
- Medicine
- Annals of neurology
- 1 December 1980
Tracer techniques and quantitative autoradiographic and tissue counting models for measurement of metabolic rates were combined with positron computed tomography (PCT) and… Expand
Positron emission tomography study of human brain functional development
- H. Chugani, M. Phelps, J. Mazziotta
- Psychology, Medicine
- Annals of neurology
- 1 October 1987
From over 100 children studied with 2‐deoxy‐2{18F}fluoro‐D‐glucose and positron emission tomography we selected 29 children (aged 5 days to 15.1 years) who had suffered transient neurological events… Expand
Tomographic measurement of local cerebral glucose metabolic rate in humans with (F‐18)2‐fluoro‐2‐deoxy‐D‐glucose: Validation of method
- M. Phelps, S. Huang, E. Hoffman, C. Selin, L. Sokoloff, D. Kuhl
- Chemistry
- 1 November 1979
Tracer techniques and quantitative autoradiographic and tissue counting models for measuremnt of metabolic rates were combined with positron computed tomography (PCT) and… Expand
Noninvasive determination of local cerebral metabolic rate of glucose in man.
- S. Huang, M. Phelps, E. Hoffman, K. Sideris, C. Selin, D. Kuhl
- Biology, Medicine
- The American journal of physiology
- 1980
A method for the determination of local cerebral metabolic rates of glucose (LCMRGlc) in normal man is described. The method employs [18F]2-fluoro-2-deoxy-D-glucose (FDG) and emission-computed… Expand
PET of brain amyloid and tau in mild cognitive impairment.
BACKGROUND
Amyloid senile plaques and tau neurofibrillary tangles are neuropathological hallmarks of Alzheimer's disease that accumulate in the cortical regions of the brain in persons with mild… Expand
Regional brain metabolic changes in patients with major depression treated with either paroxetine or interpersonal therapy: preliminary findings.
- A. Brody, S. Saxena, +11 authors L. Baxter
- Psychology, Medicine
- Archives of general psychiatry
- 1 July 2001
BACKGROUND
In functional brain imaging studies of major depressive disorder (MDD), regional abnormalities have been most commonly found in prefrontal cortex, anterior cingulate gyrus, and temporal… Expand
Quantitation in Positron Emission Computed Tomography: 1. Effect of Object Size
- E. Hoffman, S. Huang, M. Phelps
- Medicine
- Journal of computer assisted tomography
- 1 June 1979
The effect of object size on the capability of positron emission computed tomography to measure isotope concentrations in a cross section was studied. The relationship between the apparent isotope… Expand
Evaluation of the skeletal kinetics of fluorine-18-fluoride ion with PET.
- R. Hawkins, Y. Choi, +6 authors M. Phelps
- Chemistry, Medicine
- Journal of nuclear medicine : official…
- 1 May 1992
To evaluate the feasibility of quantitatively assessing regional skeletal fluoride uptake in humans in focal and generalized bone disease, we investigated the skeletal kinetics of [18F]fluoride ion… Expand
Positron emission tomography provides molecular imaging of biological processes.
- M. Phelps
- Medicine, Chemistry
- Proceedings of the National Academy of Sciences…
- 1 August 2000
Diseases are biological processes, and molecular imaging with positron emission tomography (PET) is sensitive to and informative of these processes. This is illustrated by detection of biological… Expand
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