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1-amino-1,3-dicarboxycyclopentane

Known as: ACPD (1 aminocyclopentyl 1,3 dicarboxylate), ACPD, 1-aminocyclopentane-1,3-dicarboxylic acid 
National Institutes of Health

Related topics

Related topics

6 relations

Narrower (2)

1R,3S-ACPDcis-1-amino-1,3-cyclopentanecarboxylic acid

Broader (3)

CycloleucineExcitatory Amino AcidsNeuroprotective Agents
analogs & derivatives

Papers overview

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Highly Cited
1999
Highly Cited
1999
Subthalamic Nucleus Neurons Switch from Single-Spike Activity to Burst-Firing Mode
The modification of the discharge pattern of subthalamic nucleus (STN) neurons from single-spike activity to mixed burst-firing… 
Highly Cited
1998
Highly Cited
1998
Selective abolition of the NMDA component of long-term potentiation in mice lacking mGluR5.
The mechanisms underlying the differential expression of long-term potentiation (LTP) by AMPA and NMDA receptors, are unknown… 
Highly Cited
1997
Highly Cited
1997
Mice Lacking Metabotropic Glutamate Receptor 5 Show Impaired Learning and Reduced CA1 Long-Term Potentiation (LTP) But Normal CA3 LTP
Class I metabotropic glutamate receptors (mGluRs) have been postulated to play a role in synaptic plasticity. To test the… 
Highly Cited
1997
Highly Cited
1997
A Long-Lasting Calcium-Activated Nonselective Cationic Current Is Generated by Synaptic Stimulation or Exogenous Activation of Group I Metabotropic Glutamate Receptors in CA1 Pyramidal Neurons
We have shown previously that a selective metabotropic glutamate receptor (mGluR) agonist, 1S,3R-1-aminocyclo-pentane-1,3… 
Highly Cited
1995
Highly Cited
1995
Electrical stimulation of the prefrontal cortex increases dopamine release in the nucleus accumbens of the rat: modulation by metabotropic glutamate receptors
In vivo microdialysis was used to assess the effects of electrical stimulation of the prefrontal cortex (PFC) on dopamine (DA… 
Highly Cited
1994
Highly Cited
1994
Cloning and expression of a new member of the L-2-amino-4-phosphonobutyric acid-sensitive class of metabotropic glutamate receptors.
Despite the cloning of several metabotropic glutamate receptors (mGluR1-6), the activity and localization of the cloned mGluRs do… 
Highly Cited
1992
Highly Cited
1992
3,5-Dihydroxyphenyl-glycine: a potent agonist of metabotropic glutamate receptors.
An amino acid, 3,5-dihydroxyphenylglycine (DHPG) induced current responses in Xenopus oocytes expressing a metabotropic glutamate… 
Highly Cited
1991
Highly Cited
1991
Excitatory effects of ACPD receptor activation in the hippocampus are mediated by direct effects on pyramidal cells and blockade of synaptic inhibition.
1. Phosphoinositide hydrolysis-linked excitatory amino acid (EAA) receptors (ACPD receptors) are selectively activated by the… 
Review
1990
Review
1990
Potassium conductances in hippocampal neurons blocked by excitatory amino-acid transmitters
EXCITATORY amino acids mediate fast synaptic transmission in the central nervous system through the activation of at least three… 
Highly Cited
1990
Highly Cited
1990
Messengers mediating long-term desensitization in cerebellar Purkinje cells.
Signal transduction for the characteristic long-term desensitization of glutamate receptors in Purkinje cells was investigated… 
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