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The metabotropic glutamate receptor (mGluRlα) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction
The ligand-binding domain in metabotropic glutamate receptors is related to bacterial periplasmic binding proteins
Subsynaptic segregation of metabotropic and ionotropic glutamate receptors as revealed by immunogold localization
Cloning, expression, and gene structure of a G protein-coupled glutamate receptor from rat brain.
A complementary DNA encoding a G protein-coupled glutamate receptor from rat brain, GluGR, was cloned by functional expression in Xenopus oocytes, suggesting that it may be a member of a new subfamily.
Cloning and expression of a new member of the L-2-amino-4-phosphonobutyric acid-sensitive class of metabotropic glutamate receptors.
- J. Saugstad, J. Kinzie, E. Mulvihill, T. Segerson, G. Westbrook
- BiologyMolecular pharmacology
- 1 March 1994
The expression pattern and L-AP4 sensitivity of mGluR7 suggest that it mediates inhibition of transmitter release at selected glutamatergic synapses, and the coexpression of multiple mGLUR mRNAs in single neurons indicates that the cellular effects of m GluR activation are likely to result from the integrated action of several receptor subtypes.
A pharmacological characterization of the mGluR1α subtype of the metabotropic glutamate receptor expressed in a cloned baby hamster kidney cell line
Formation of stable preinitiation complexes between eukaryotic class B transcription factors and promoter sequences
At least one of the HeLa cell factors necessary for correct in vitro transcription from conalbumin or adenovirus late promoters binds to the region of the template that contains the ‘TATA’ box, which results in the formation of stable preinitiation complexes.
Relationship of nuclear estrogen receptor levels to induction of ovalbumin and conalbumin mRNA in chick oviduct.
L-2-amino-4-phosphonobutyrate (L-AP4) is an agonist at the type iv metabotropic glutamate receptor which is negatively coupled to adenylate cyclase