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Glial and neuronal control of brain blood flow
TLDR
It is now recognized that neurotransmitter-mediated signalling has a key role in regulating cerebral blood flow, that much of this control is mediated by astrocytes, that oxygen modulates blood flow regulation, and that blood flow may be controlled by capillaries as well as by arterioles. Expand
Glutamate Released from Glial Cells Synchronizes Neuronal Activity in the Hippocampus
TLDR
It is demonstrated in hippocampal slices of 2- to 5-week-old rats that glutamate released from glial cells generates slow transient currents (STCs) mediated by the activation of NMDA receptors in pyramidal cells, indicating a nonsynaptic origin of the source of glutamate. Expand
External Tufted Cells Drive the Output of Olfactory Bulb Glomeruli
TLDR
It is proposed that ET cells act as essential drivers of glomerular output to the olfactory cortex, and mediate feedforward excitation of mitral cells within the same glomerulus. Expand
Two types of nicotinic receptors mediate an excitation of neocortical layer I interneurons.
TLDR
The results suggest that acetylcholine released in layer I may induce a disinhibition of the cortical network through activation of nicotinic receptors expressed by layer I interneurons. Expand
Target cell-specific modulation of neuronal activity by astrocytes.
TLDR
In the rat olfactory bulb, it is demonstrated that the release of GABA by astrocytes causes long-lasting and synchronous inhibition of mitral and granule cells. Expand
Appearance and transient expression of oxytocin receptors in fetal, infant, and peripubertal rat brain studied by autoradiography and electrophysiology
TLDR
It is suggested that OT binding sites detected by autoradiography in the developing rat brain represent, at least in some areas, functional neuronal receptors. Expand
Intraglomerular Lateral Inhibition Promotes Spike Timing Variability in Principal Neurons of the Olfactory Bulb
TLDR
Paired recording in olfactory bulb slices and two-photon targeted patch-clamp recording in vivo is used to characterize the properties and connections of a genetically identified population of PG cells expressing enhanced yellow fluorescent protein (EYFP) under the control of the Kv3.1 potassium channel promoter. Expand
Potassium conductances in hippocampal neurons blocked by excitatory amino-acid transmitters
TLDR
Electrophysio-logical consequences of the metabotropic response closely resemble those induced by activating muscarinic acetylcholine receptors in the same neurons and suggest that excitatory amino acids not only act as fast ionotropic transmitters but also as slow neuromodulatory transmitters. Expand
Calcium dynamics in astrocyte processes during neurovascular coupling
TLDR
It is shown that in anesthetized mice, the physiological activation of olfactory sensory neuron (OSN) terminals reliably triggers Ca2+ increases in astrocyte processes but not in somata, reestablishingAstrocytes as potential regulators of neurovascular coupling. Expand
Monosynaptic and Polysynaptic Feed-Forward Inputs to Mitral Cells from Olfactory Sensory Neurons
TLDR
It is demonstrated that stimulation of OSNs produces a biphasic postsynaptic excitatory response in mitral cells, and OSN stimulation triggers a strong and slow feedforward inhibition that shapes the feedforward excitation but leaves unaffected the monosynaptic component. Expand
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