zolmitriptan

Known as: zolmitriptan [Chemical/Ingredient], (S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one, 4-[[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-one 
A member of the triptan class of agents with anti-migraine properties. Zolmitriptan selectively binds to and activates serotonin (5-HT) 1B receptors… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
BACKGROUND Calcitonin gene-related peptide (CGRP) probably has a role in migraine pathophysiology, and antagonism of its… (More)
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2007
2007
OBJECTIVE The goal was to evaluate the efficacy and tolerability of zolmitriptan nasal spray in the treatment of adolescent… (More)
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2006
2006
BACKGROUND Cluster headache is a form of primary headache in which attacks are rapid in onset with very severe pain. The… (More)
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2006
2006
OBJECTIVE The objective of this randomized, double-blind, placebo-controlled study was to evaluate the efficacy and tolerability… (More)
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2005
2005
The aim of this investigation was to prepare microemulsions containing zolmitriptan (ZT) for rapid drug delivery to the brain to… (More)
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2005
2005
A gradient, reversed-phase liquid chromatographic (RP-LC) assay method was developed for the quantitative determination of… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND The triptans, selective serotonin 5-HT(1B/1D) agonists, are very effective acute migraine drugs with a well- developed… (More)
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2000
2000
Data from a subgroup of adolescents (12-17 years) entered into a one-year open-label phase of a large international study were… (More)
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2000
2000
OBJECTIVE To evaluate the efficacy and tolerability of oral zolmitriptan 5 mg and 10 mg and placebo in cluster headache… (More)
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2000
2000
The efficacy and tolerability of rizatriptan (MAXALT) and zolmitriptan (ZOMIG) were compared in a randomized, double-blind… (More)
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