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311C90

 
National Institutes of Health

Papers overview

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Highly Cited
1997
Highly Cited
1997
The trigeminovascular system consists of bipolar neurons which innervate pain-sensitive intracranial structures and projecting to… Expand
Highly Cited
1997
Highly Cited
1997
  • G. Martin, A D Robertson, +6 authors S. Moncada
  • British journal of pharmacology
  • 1997
  • Corpus ID: 37411640
311C90 (zolmitriptan zomig: (S)‐4[[3‐[2‐(dimethylamino)ethyl]‐1H‐indol‐5‐yl]methyl]‐2‐oxazolidinone) is a novel 5‐HT1B/1D… Expand
Highly Cited
1997
Highly Cited
1997
As shown in animal studies, 5HT1B/1D agonists can inhibit activity in the trigeminal nucleus caudalis, which may be advantageous… Expand
Highly Cited
1997
Highly Cited
1997
AIMS Two open studies in healthy volunteers were conducted to determine the absolute bioavailability and metabolic disposition of… Expand
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Highly Cited
1996
Highly Cited
1996
&NA; Migraine is a common and debilitating condition. Its treatment has received considerable attention in recent times with the… Expand
Highly Cited
1996
Highly Cited
1996
311C90 is a novel, centrally and peripherally, acting 5-hydroxytryptamine (1D) receptor agonist. We investigated the efficacy and… Expand
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Highly Cited
1996
Highly Cited
1996
1. 311C90 is a novel and selective agonist at 5-HT1D receptors, with central and peripheral actions, currently in development for… Expand
Highly Cited
1996
Highly Cited
1996
The oral absorption of a 10-m. oral dose of the novel 5-hydroxytryptamine (5HT1D) agonist, 311C90, was compared during a moderate… Expand
1994
1994
Migraine headache involves the activation of trigeminal afferents that are predominantly found in the first or ophthalmic… Expand