311C90
National Institutes of Health
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The trigeminovascular system consists of bipolar neurons which innervate pain-sensitive intracranial structures and projecting to…
311C90 (zolmitriptan zomig: (S)‐4[[3‐[2‐(dimethylamino)ethyl]‐1H‐indol‐5‐yl]methyl]‐2‐oxazolidinone) is a novel 5‐HT1B/1D…
AIMS
Two open studies in healthy volunteers were conducted to determine the absolute bioavailability and metabolic disposition of…
311C90 is a novel, centrally and peripherally, acting 5-hydroxytryptamine (1D) receptor agonist. We investigated the efficacy and…
1. 311C90 is a novel and selective agonist at 5-HT1D receptors, with central and peripheral actions, currently in development for…
The oral absorption of a 10-m. oral dose of the novel 5-hydroxytryptamine (5HT1D) agonist, 311C90, was compared during a moderate…
Migraine headache involves the activation of trigeminal afferents that are predominantly found in the first or ophthalmic…