Oxazolidinones

Known as: Oxazolidinones [Chemical/Ingredient], oxazolidinone 
Derivatives of oxazolidin-2-one. They represent an important class of synthetic antibiotic agents.
National Institutes of Health

Papers overview

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Review
2011
Review
2011
The success of linezolid stimulated significant efforts to discover new agents in the oxazolidinone class. Over a dozen… (More)
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Highly Cited
2009
Highly Cited
2009
TR-700 (torezolid), the active moiety of the novel oxazolidinone phosphate prodrug TR-701, is highly potent against gram-positive… (More)
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Highly Cited
2008
Highly Cited
2008
The oxazolidinones represent the first new class of antibiotics to enter into clinical usage within the past 30 years, but their… (More)
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Highly Cited
2006
Highly Cited
2006
A novel multidrug resistance phenotype mediated by the Cfr rRNA methyltransferase is observed in Staphylococcus aureus and… (More)
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Highly Cited
2006
Highly Cited
2006
The effects of a variety of oxazolidinones, with different antibacterial potencies, including linezolid, on mitochondrial protein… (More)
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Review
2004
Review
2004
Oxazolidinones are a new group of antibiotics. These synthetic drugs are active against a large spectrum of Gram-positive… (More)
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Review
2001
Review
2001
Many common gram-positive pathogens (eg, Staphylococcus aureus, Enterococcus spp, and Streptococcus pneumoniae) have become… (More)
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Highly Cited
1999
Highly Cited
1999
The activities of linezolid, eperezolid, and PNU-100480 were evaluated in a murine model of tuberculosis. Approximately 10(7… (More)
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Highly Cited
1998
Highly Cited
1998
The oxazolidinones represent a new class of antimicrobial agents which are active against multidrug-resistant staphylococci… (More)
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Highly Cited
1996
Highly Cited
1996
Oxazolidinones make up a relatively new class of antimicrobial agents which possess a unique mechanism of bacterial protein… (More)
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