tyrphostin AG 1478

Known as: AG 1478, RTKI cpd, tyrphostin-AG1478 
A member of the tyrphostin family of tyrosine kinase inhibitors, that selectively inhibits epidermal growth factor. (NCI)
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
Fifteen percent of lung cancer cases occur in never-smokers and show characteristics that are molecularly and clinically distinct… (More)
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Highly Cited
2006
Highly Cited
2006
The molecular bridges that link the LH surge with functional changes in cumulus cells that possess few LH receptors are being… (More)
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Highly Cited
2003
Highly Cited
2003
Estradiol (E2) rapidly stimulates signal transduction from plasma membrane estrogen receptors (ER) that are G protein-coupled… (More)
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Highly Cited
2002
Highly Cited
2002
Overexpression of the epidermal growth factor receptor (EGFR) has been shown previously to correlate with enhanced malignant… (More)
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Highly Cited
2002
Highly Cited
2002
Binding of ouabain to Na(+)/K(+)-ATPase activates tyrosine phosphorylation of the epidermal growth factor receptor (EGFR), Src… (More)
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Highly Cited
2000
Highly Cited
2000
HER2/neu (erbB-2) overexpression has been causally associated with tamoxifen resistance in human breast cancer cells. Forced… (More)
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Highly Cited
1998
Highly Cited
1998
Adhesion of human primary skin fibroblasts and ECV304 endothelial cells to immobilized matrix proteins, beta1 or alphav integrin… (More)
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Highly Cited
1997
Highly Cited
1997
Accelerated cellular repopulation has been described as a response of tumors to fractionated irradiation in both normal tissue… (More)
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1996
1996
The effects of a new epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, tyrphostin AG 1478, were tested on three… (More)
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Highly Cited
1996
Highly Cited
1996
TRANSDUCTION of a mitogenic signal from the cell membrane to the nucleus involves the adapter proteins SHC and Grb2, which… (More)
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