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Receptor Tyrosine Kinase Inhibition

Known as: Tyrosine Kinase Receptor Inhibition 
A process that negatively regulates the intracellular catalytic activities that originate with the binding of a tyrosine kinase-associated… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
02419902018

Related topics

Related topics

50 relations
ALK/FAK/Pyk2 Inhibitor CT-707ALK/TRK Inhibitor TSR-011ASP3026AXL Inhibitor BGB324
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Related mentions per year

Related mentions per year

1955-2018
1960198020002020
Receptor Tyrosine Kinase Inhibition
imatinib
Protein-tyrosine kinase inhibitor
Ibrutinib
Vandetanib
tyrphostin 25

Papers overview

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2012
2012
Mer receptor tyrosine kinase inhibition impedes glioblastoma multiforme migration and alters cellular morphology
Glioblastoma multiforme (GBM) is an aggressive brain tumor, fatal within 1 year from diagnosis in most patients despite intensive… (More)
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2011
2011
Compensatory effects in the PI3K/PTEN/AKT signaling network following receptor tyrosine kinase inhibition.
Overcoming de novo and acquired resistance to anticancer drugs that target signaling networks is a formidable challenge for drug… (More)
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Highly Cited
2006
Highly Cited
2006
Methylnaltrexone inhibits opiate and VEGF-induced angiogenesis: role of receptor transactivation.
Angiogenesis or the formation of new blood vessels is important in the growth and metastatic potential of various cancers… (More)
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Highly Cited
2006
Highly Cited
2006
IGF-1 receptor tyrosine kinase inhibition by the cyclolignan PPP induces G2/M-phase accumulation and apoptosis in multiple myeloma cells.
Emerging evidence suggests the insulin-like growth factor-1 receptor (IGF-1R) to be an important mediator of tumor-cell survival… (More)
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2005
2005
Enhanced susceptibility of irradiated tumor vessels to vascular endothelial growth factor receptor tyrosine kinase inhibition.
Previous experiments with PTK787/ZK222584, a specific inhibitor of vascular endothelial growth factor receptor (VEGFR) tyrosine… (More)
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2004
2004
Epidermal growth factor receptor tyrosine kinase inhibition represses cyclin D1 in aerodigestive tract cancers.
PURPOSE Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are active in cancer therapy. Mechanisms… (More)
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Highly Cited
2003
Highly Cited
2003
EGF receptor tyrosine kinase inhibition attenuates the development of PKD in Han:SPRD rats.
BACKGROUND Increasing evidence supports an important role for the epidermal growth factor (EGF)/transforming growth factor-alpha… (More)
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2003
2003
Epidermal growth factor receptor tyrosine kinase inhibition augments a murine model of pulmonary fibrosis.
The inappropriate regeneration of sequentially injured epithelium is an important process leading to pulmonary fibrosis. Previous… (More)
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2002
2002
Effect of epidermal growth factor receptor tyrosine kinase inhibition on epithelial proliferation in normal and premalignant breast.
The factors controlling epithelial proliferation in ductal carcinoma in situ (DCIS) are unclear. Antiestrogens are effective in… (More)
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1997
1997
EGF-receptor tyrosine kinase inhibition induces keratinocyte growth arrest and terminal differentiation.
Epidermal keratinocyte growth and differentiation are regulated by specific families of growth factors and receptors. Peptide… (More)
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