Receptor Tyrosine Kinase Inhibition

Known as: Tyrosine Kinase Receptor Inhibition 
A process that negatively regulates the intracellular catalytic activities that originate with the binding of a tyrosine kinase-associated… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
02419902018

Papers overview

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2012
2012
Glioblastoma multiforme (GBM) is an aggressive brain tumor, fatal within 1 year from diagnosis in most patients despite intensive… (More)
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2011
2011
Overcoming de novo and acquired resistance to anticancer drugs that target signaling networks is a formidable challenge for drug… (More)
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Highly Cited
2006
Highly Cited
2006
Angiogenesis or the formation of new blood vessels is important in the growth and metastatic potential of various cancers… (More)
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Highly Cited
2006
Highly Cited
2006
Emerging evidence suggests the insulin-like growth factor-1 receptor (IGF-1R) to be an important mediator of tumor-cell survival… (More)
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2005
2005
Previous experiments with PTK787/ZK222584, a specific inhibitor of vascular endothelial growth factor receptor (VEGFR) tyrosine… (More)
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2004
2004
PURPOSE Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are active in cancer therapy. Mechanisms… (More)
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2003
Highly Cited
2003
BACKGROUND Increasing evidence supports an important role for the epidermal growth factor (EGF)/transforming growth factor-alpha… (More)
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2003
2003
The inappropriate regeneration of sequentially injured epithelium is an important process leading to pulmonary fibrosis. Previous… (More)
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2002
2002
The factors controlling epithelial proliferation in ductal carcinoma in situ (DCIS) are unclear. Antiestrogens are effective in… (More)
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1997
1997
Epidermal keratinocyte growth and differentiation are regulated by specific families of growth factors and receptors. Peptide… (More)
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