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Receptor Tyrosine Kinase Inhibition
Known as:
Tyrosine Kinase Receptor Inhibition
A process that negatively regulates the intracellular catalytic activities that originate with the binding of a tyrosine kinase-associated…
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National Institutes of Health
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Related topics
Related topics
50 relations
AXL Inhibitor BGB324
Allosteric Bcr-Abl Tyrosine Kinase Inhibitor ABL001
BMS 599626
BMS 777607
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Bypass Mechanisms of Resistance to Receptor Tyrosine Kinase Inhibition in Lung Cancer
M. Niederst
,
J. Engelman
Science Signaling
2013
Corpus ID: 2678392
The mechanisms mediating kinase inhibitor resistance in lung cancer are reviewed. Gloss In various cancers, somatic alterations…
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Highly Cited
2012
Highly Cited
2012
Mer receptor tyrosine kinase inhibition impedes glioblastoma multiforme migration and alters cellular morphology
A. Rogers
,
J. Le
,
+4 authors
A. Keating
Oncogene
2012
Corpus ID: 25424200
Glioblastoma multiforme (GBM) is an aggressive brain tumor, fatal within 1 year from diagnosis in most patients despite intensive…
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Highly Cited
2006
Highly Cited
2006
Methylnaltrexone inhibits opiate and VEGF-induced angiogenesis: role of receptor transactivation.
P. Singleton
,
M. Lingen
,
M. Fekete
,
J. Garcia
,
J. Moss
Microvascular research
2006
Corpus ID: 2042083
Highly Cited
2006
Highly Cited
2006
IGF-1 receptor tyrosine kinase inhibition by the cyclolignan PPP induces G2/M-phase accumulation and apoptosis in multiple myeloma cells.
T. Strömberg
,
S. Ekman
,
+10 authors
H. Jernberg-Wiklund
Blood
2006
Corpus ID: 18797782
Emerging evidence suggests the insulin-like growth factor-1 receptor (IGF-1R) to be an important mediator of tumor-cell survival…
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Highly Cited
2004
Highly Cited
2004
BDNF is necessary and sufficient for spinal respiratory plasticity following intermittent hypoxia
T. Baker-Herman
,
D. Fuller
,
+6 authors
G. Mitchell
Nature Neuroscience
2004
Corpus ID: 22965093
Intermittent hypoxia causes a form of serotonin-dependent synaptic plasticity in the spinal cord known as phrenic long-term…
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Highly Cited
2004
Highly Cited
2004
Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition Represses Cyclin D1 in Aerodigestive Tract Cancers
W. J. Petty
,
K. Dragnev
,
+10 authors
E. Dmitrovsky
Clinical Cancer Research
2004
Corpus ID: 287109
Purpose: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are active in cancer therapy. Mechanisms…
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Highly Cited
2003
Highly Cited
2003
EGF receptor tyrosine kinase inhibition attenuates the development of PKD in Han:SPRD rats.
V. Torres
,
W. Sweeney
,
+4 authors
E. Avner
Kidney international
2003
Corpus ID: 28059774
BACKGROUND Increasing evidence supports an important role for the epidermal growth factor (EGF)/transforming growth factor-alpha…
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Highly Cited
2003
Highly Cited
2003
Epidermal growth factor receptor tyrosine kinase inhibition augments a murine model of pulmonary fibrosis.
Hiroko Suzuki
,
K. Aoshiba
,
N. Yokohori
,
A. Nagai
Cancer research
2003
Corpus ID: 10012338
The inappropriate regeneration of sequentially injured epithelium is an important process leading to pulmonary fibrosis. Previous…
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Highly Cited
2002
Highly Cited
2002
Effect of epidermal growth factor receptor tyrosine kinase inhibition on epithelial proliferation in normal and premalignant breast.
K. Chan
,
W. F. Knox
,
+4 authors
N. Bundred
Cancer research
2002
Corpus ID: 2331170
The factors controlling epithelial proliferation in ductal carcinoma in situ (DCIS) are unclear. Antiestrogens are effective in…
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Highly Cited
1997
Highly Cited
1997
EGF-receptor tyrosine kinase inhibition induces keratinocyte growth arrest and terminal differentiation.
D. Peus
,
L. Hamacher
,
M. Pittelkow
The Journal of investigative dermatology
1997
Corpus ID: 8318967
Epidermal keratinocyte growth and differentiation are regulated by specific families of growth factors and receptors. Peptide…
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