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Receptor Tyrosine Kinase Inhibition

Known as: Tyrosine Kinase Receptor Inhibition 
A process that negatively regulates the intracellular catalytic activities that originate with the binding of a tyrosine kinase-associated… Expand
National Institutes of Health

Related topics

Related topics

50 relations
AXL Inhibitor BGB324Allosteric Bcr-Abl Tyrosine Kinase Inhibitor ABL001BMS 599626BMS 777607
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Crosstalk with cancer-associated fibroblasts induces resistance of non-small cell lung cancer cells to epidermal growth factor receptor tyrosine kinase inhibition
Although lung cancers with activating mutations in the epidermal growth factor receptor (EGFR) are highly sensitive to selective… Expand
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2012
2012
Mer receptor tyrosine kinase inhibition impedes glioblastoma multiforme migration and alters cellular morphology
Glioblastoma multiforme (GBM) is an aggressive brain tumor, fatal within 1 year from diagnosis in most patients despite intensive… Expand
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2008
2008
Vertical VEGF targeting: A combination of ligand blockade with receptor tyrosine kinase inhibition.
The aim of this study was to examine the anti-tumour effects of dual vertical VEGF targeting consisting in the association… Expand
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Highly Cited
2006
Highly Cited
2006
IGF-1 receptor tyrosine kinase inhibition by the cyclolignan PPP induces G2/M-phase accumulation and apoptosis in multiple myeloma cells.
Emerging evidence suggests the insulin-like growth factor-1 receptor (IGF-1R) to be an important mediator of tumor-cell survival… Expand
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Highly Cited
2004
Highly Cited
2004
BDNF is necessary and sufficient for spinal respiratory plasticity following intermittent hypoxia
Intermittent hypoxia causes a form of serotonin-dependent synaptic plasticity in the spinal cord known as phrenic long-term… Expand
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Highly Cited
2004
Highly Cited
2004
Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition Represses Cyclin D1 in Aerodigestive Tract Cancers
Purpose: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are active in cancer therapy. Mechanisms… Expand
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Highly Cited
2003
Highly Cited
2003
EGF receptor tyrosine kinase inhibition attenuates the development of PKD in Han:SPRD rats.
BACKGROUND Increasing evidence supports an important role for the epidermal growth factor (EGF)/transforming growth factor-alpha… Expand
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Highly Cited
2003
Highly Cited
2003
Epidermal growth factor receptor tyrosine kinase inhibition augments a murine model of pulmonary fibrosis.
The inappropriate regeneration of sequentially injured epithelium is an important process leading to pulmonary fibrosis. Previous… Expand
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Highly Cited
2002
Highly Cited
2002
Effect of epidermal growth factor receptor tyrosine kinase inhibition on epithelial proliferation in normal and premalignant breast.
The factors controlling epithelial proliferation in ductal carcinoma in situ (DCIS) are unclear. Antiestrogens are effective in… Expand
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Highly Cited
1997
Highly Cited
1997
EGF-receptor tyrosine kinase inhibition induces keratinocyte growth arrest and terminal differentiation.
Epidermal keratinocyte growth and differentiation are regulated by specific families of growth factors and receptors. Peptide… Expand
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