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Receptor Tyrosine Kinase Inhibition

Known as: Tyrosine Kinase Receptor Inhibition 
A process that negatively regulates the intracellular catalytic activities that originate with the binding of a tyrosine kinase-associated… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Glioblastoma multiforme (GBM) is an aggressive brain tumor, fatal within 1 year from diagnosis in most patients despite intensive… Expand
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2008
2008
The aim of this study was to examine the anti-tumour effects of dual vertical VEGF targeting consisting in the association… Expand
Highly Cited
2006
Highly Cited
2006
Emerging evidence suggests the insulin-like growth factor-1 receptor (IGF-1R) to be an important mediator of tumor-cell survival… Expand
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Highly Cited
2004
Highly Cited
2004
Intermittent hypoxia causes a form of serotonin-dependent synaptic plasticity in the spinal cord known as phrenic long-term… Expand
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Highly Cited
2004
Highly Cited
2004
Purpose: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are active in cancer therapy. Mechanisms… Expand
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Advances in the understanding of cystogenesis, identification of the PKHD1 gene and availability of a rat model (the… Expand
Highly Cited
2003
Highly Cited
2003
BACKGROUND Increasing evidence supports an important role for the epidermal growth factor (EGF)/transforming growth factor-alpha… Expand
Highly Cited
2003
Highly Cited
2003
The inappropriate regeneration of sequentially injured epithelium is an important process leading to pulmonary fibrosis. Previous… Expand
Highly Cited
2002
Highly Cited
2002
The factors controlling epithelial proliferation in ductal carcinoma in situ (DCIS) are unclear. Antiestrogens are effective in… Expand
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Highly Cited
1997
Highly Cited
1997
Epidermal keratinocyte growth and differentiation are regulated by specific families of growth factors and receptors. Peptide… Expand