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tyrphostin 25

Known as: 4,5-Trihydroxybenzylidene malononitrile, Tyrphostin A25, tyrphostin-25 
A member of the tyrphostin family of tyrosine kinase inhibitors that competitively binds and inhibits epidermal growth factor receptor and GTPase… 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (4)

Antineoplastic AgentsEnzyme InhibitorsNitrilesTyrphostins
Receptor Tyrosine Kinase Inhibition

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
The induction of the human hepatic CYP2E1 gene by interleukin 4 is transcriptional and regulated by protein kinase C
Cytochrome P4502E1 (CYP2E1) plays a key role in the metabolism of numerous drug substrates, mostly in mammalian liver. Both the… 
2000
2000
Down-regulation of L-selectin Expression in Neutrophils by Nonsteroidal Anti-Inflammatory Drugs: Role of Intracellular ATP Concentration
L-selectin is an adhesion molecule that plays an essential role in the early events of the inflammatory response. Our group has… 
1999
1999
Interaction of Islet Hormones with Cholecystokinin Octapeptide‐Evoked Secretory Responses in the Isolated Pancreas of Normal and Diabetic Rats
This study investigates the effects of the islet hormones, insulin (Ins), glucagon (Glu) and somatostatin (Som) with… 
1998
1998
Effect of basic fibroblast growth factor on cholecystokinin-induced amylase release and intracellular calcium increase in male rat pancreatic acinar cells.
1998
1998
Pharmacological and Functional Characterization of Muscarinic Receptors in the Frog Pars Intermedia1
The secretion of αMSH from the intermediate lobe of the frog pituitary is regulated by multiple factors, including classical… 
1998
1998
Asbestos-induced lung epithelial permeability: potential role of nonoxidant pathways.
Asbestos fibers are an important cause of lung fibrosis; however, the biological mechanisms are incompletely understood. The lung… 
1997
1997
Effect of protein kinase inhibitors on activity of mammalian small heat-shock protein (HSP25) kinase.
1997
1997
Characterization of the acetylcholine-reducing effect of the amyloid-β peptide in mouse SN56 cells
Highly Cited
1996
Highly Cited
1996
Formation of nascent secretory vesicles from the trans-Golgi network of endocrine cells is inhibited by tyrosine kinase and phosphatase inhibitors
Recent evidence suggests that secretory vesicle formation from the TGN is regulated by cytosolic signaling pathways involving… 
1996
1996
Neuropeptides stimulate tyrosine phosphorylation and tyrosine kinase activity in small cell lung cancer cell lines
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