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tyrphostin 25
Known as:
4,5-Trihydroxybenzylidene malononitrile
, Tyrphostin A25
, tyrphostin-25
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A member of the tyrphostin family of tyrosine kinase inhibitors that competitively binds and inhibits epidermal growth factor receptor and GTPase…
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National Institutes of Health
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Related topics
Related topics
5 relations
Broader (4)
Antineoplastic Agents
Enzyme Inhibitors
Nitriles
Tyrphostins
Receptor Tyrosine Kinase Inhibition
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Perivascular adipose tissue promotes vasoconstriction: the role of superoxide anion.
Yu-Jing Gao
,
K. Takemori
,
+4 authors
R. M. Lee
Cardiovascular Research
2006
Corpus ID: 16149255
Highly Cited
2004
Highly Cited
2004
Mechanisms of ADRF release from rat aortic adventitial adipose tissue.
G. Dubrovska
,
S. Verlohren
,
F. Luft
,
M. Gollasch
American Journal of Physiology. Heart and…
2004
Corpus ID: 11349372
Blood vessels are surrounded by variable amounts of adipose tissue. We showed earlier that adventitial adipose tissue inhibits…
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Highly Cited
2003
Highly Cited
2003
Fibronectin Fragment Activation of Proline-rich Tyrosine Kinase PYK2 Mediates Integrin Signals Regulating Collagenase-3 Expression by Human Chondrocytes through a Protein Kinase C-dependent Pathway*
R. Loeser
,
C. Forsyth
,
A. Samarel
,
H. Im
Journal of Biological Chemistry
2003
Corpus ID: 21825173
Fibronectin fragments (FN-f), including the 110-kDa fragment that binds the α5β1 integrin, stimulate collagenase-3 (MMP-13…
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Highly Cited
2000
Highly Cited
2000
Intestinal trefoil factor confers colonic epithelial resistance to apoptosis.
D. Taupin
,
K. Kinoshita
,
D. Podolsky
Proceedings of the National Academy of Sciences…
2000
Corpus ID: 25990287
Intestinal trefoil factor (ITF) is an essential regulator of colonic epithelial restitution, the rapid migration of colonocytes…
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Highly Cited
2000
Highly Cited
2000
Autophagic and apoptotic types of programmed cell death exhibit different fates of cytoskeletal filaments.
W. Bursch
,
K. Hochegger
,
L. Torok
,
B. Marian
,
A. Ellinger
,
R. S. Hermann
Journal of Cell Science
2000
Corpus ID: 8696008
Programmed cell death comprises several subtypes, as revealed by electron microscopy. Apoptosis or type I programmed cell death…
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Highly Cited
1996
Highly Cited
1996
Tyrosine phosphorylation of pp125FAK and paxillin in aortic endothelial cells induced by mechanical strain.
Y. Yano
,
J. Geibel
,
B. Sumpio
American Journal of Physiology
1996
Corpus ID: 42848487
The objective of this study was to determine whether focal adhesion proteins pp125FAK (focal adhesion kinase) and paxillin are…
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Highly Cited
1996
Highly Cited
1996
Genistein inhibits both estrogen and growth factor-stimulated proliferation of human breast cancer cells.
G. Peterson
,
S. Barnes
Cell growth & differentiation : the molecular…
1996
Corpus ID: 22135921
Genistein is a naturally occurring dietary protein tyrosine kinase (PTK) inhibitor that is hypothesized to be responsible for the…
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Highly Cited
1996
Highly Cited
1996
Substance P-induced mitogenesis in human astrocytoma cells correlates with activation of the mitogen-activated protein kinase signaling pathway.
W. Luo
,
T. Sharif
,
M. Sharif
Cancer Research
1996
Corpus ID: 35155581
The neuropeptide substance P (SP) regulates many biological processes through binding to and activating the SP receptor (NK-1…
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Highly Cited
1994
Highly Cited
1994
Receptor tyrosine kinase signaling required for integrin alpha v beta 5- directed cell motility but not adhesion on vitronectin
R. Klemke
,
M. Yebra
,
E. Bayna
,
D. Cheresh
Journal of Cell Biology
1994
Corpus ID: 18388118
FG human pancreatic carcinoma cells adhere to vitronectin using integrin alpha v beta 5 yet are unable to migrate on this ligand…
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Highly Cited
1993
Highly Cited
1993
Genistein and biochanin A inhibit the growth of human prostate cancer cells but not epidermal growth factor receptor tyrosine autophosphorylation
G. Peterson
,
S. Barnes
The Prostate
1993
Corpus ID: 45202025
The effect of the isoflavones, genistein, daidzein, and biochanin A on the growth of the LNCaP and DU‐145 human prostate cancer…
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