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tyrphostin 25

Known as: 4,5-Trihydroxybenzylidene malononitrile, Tyrphostin A25, tyrphostin-25 
A member of the tyrphostin family of tyrosine kinase inhibitors that competitively binds and inhibits epidermal growth factor receptor and GTPase… Expand
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
OBJECTIVES Recent studies have demonstrated that perivascular adipose tissue (PVAT) releases vascular relaxation factor(s). In… Expand
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Highly Cited
2004
Highly Cited
2004
Blood vessels are surrounded by variable amounts of adipose tissue. We showed earlier that adventitial adipose tissue inhibits… Expand
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Highly Cited
2003
Highly Cited
2003
Fibronectin fragments (FN-f), including the 110-kDa fragment that binds the α5β1 integrin, stimulate collagenase-3 (MMP-13… Expand
Highly Cited
2000
Highly Cited
2000
Intestinal trefoil factor (ITF) is an essential regulator of colonic epithelial restitution, the rapid migration of colonocytes… Expand
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Highly Cited
2000
Highly Cited
2000
Programmed cell death comprises several subtypes, as revealed by electron microscopy. Apoptosis or type I programmed cell death… Expand
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Highly Cited
1996
Highly Cited
1996
Genistein is a naturally occurring dietary protein tyrosine kinase (PTK) inhibitor that is hypothesized to be responsible for the… Expand
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Highly Cited
1996
Highly Cited
1996
The objective of this study was to determine whether focal adhesion proteins pp125FAK (focal adhesion kinase) and paxillin are… Expand
Highly Cited
1996
Highly Cited
1996
The neuropeptide substance P (SP) regulates many biological processes through binding to and activating the SP receptor (NK-1… Expand
Highly Cited
1994
Highly Cited
1994
The effect of several tyrosine kinase inhibitors was tested on Ca2+ influx mediated by thapsigargin-and CCh-induced intracellular… Expand
Highly Cited
1993
Highly Cited
1993
The effect of the isoflavones, genistein, daidzein, and biochanin A on the growth of the LNCaP and DU‐145 human prostate cancer… Expand