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tyrphostin 25

Known as: 4,5-Trihydroxybenzylidene malononitrile, Tyrphostin A25, tyrphostin-25 
A member of the tyrphostin family of tyrosine kinase inhibitors that competitively binds and inhibits epidermal growth factor receptor and GTPase… Expand
National Institutes of Health

Related topics

Related topics

5 relations

Broader (4)

Antineoplastic AgentsEnzyme InhibitorsNitrilesTyrphostins
Receptor Tyrosine Kinase Inhibition

Papers overview

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Highly Cited
2006
Highly Cited
2006
Perivascular adipose tissue promotes vasoconstriction: the role of superoxide anion.
OBJECTIVES Recent studies have demonstrated that perivascular adipose tissue (PVAT) releases vascular relaxation factor(s). In… Expand
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2003
2003
Galectin-3 expression in macrophages is signaled by Ras/MAP kinase pathway and up-regulated by modified lipoproteins.
To study the signaling pathway involved in the regulation of galectin-3 expression we used phorbol ester to stimulate macrophage… Expand
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2003
2003
Tyrosine phosphorylation of the Rab24 GTPase in cultured mammalian cells.
Several members of the large family of Rab GTPases have been shown to function in vesicular trafficking in mammalian cells… Expand
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2003
2003
Arsenite stimulated glucose transport in 3T3-L1 adipocytes involves both Glut4 translocation and p38 MAPK activity.
The protein-modifying agent arsenite stimulates glucose uptake in 3T3-L1 adipocytes. In the current study we have analysed the… Expand
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2001
2001
Genistein, a soybean isoflavone, inhibits inward rectifier K(+) channels in rat osteoclasts.
Genistein, a soybean-derived isoflavone with an inhibitory effect on protein tyrosine kinases (PTKs), has been shown to suppress… Expand
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Highly Cited
2000
Highly Cited
2000
Intestinal trefoil factor confers colonic epithelial resistance to apoptosis.
Intestinal trefoil factor (ITF) is an essential regulator of colonic epithelial restitution, the rapid migration of colonocytes… Expand
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1998
1998
Constitutively active Galpha12, Galpha13, and Galphaq induce Rho-dependent neurite retraction through different signaling pathways.
In neuronal cells, activation of a certain heterotrimeric G protein-coupled receptor causes neurite retraction and cell rounding… Expand
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1998
1998
Tyrosine kinase inhibitor effects on avian osteoclastic acid transport.
We found that tyrosine kinase pp60(c-src) coisolates with acid-transporting osteoclast membranes and hypothesized that this… Expand
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Highly Cited
1994
Highly Cited
1994
Receptor tyrosine kinase signaling required for integrin alpha v beta 5- directed cell motility but not adhesion on vitronectin
FG human pancreatic carcinoma cells adhere to vitronectin using integrin alpha v beta 5 yet are unable to migrate on this ligand… Expand
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Highly Cited
1993
Highly Cited
1993
Genistein and biochanin A inhibit the growth of human prostate cancer cells but not epidermal growth factor receptor tyrosine autophosphorylation.
The effect of the isoflavones, genistein, daidzein, and biochanin A on the growth of the LNCaP and DU-145 human prostate cancer… Expand
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