Tyrphostins

Known as: Tyrphostins [Chemical/Ingredient], tyrphostin 
A family of synthetic protein tyrosine kinase inhibitors. They selectively inhibit receptor autophosphorylation and are used to study receptor… (More)
National Institutes of Health

Papers overview

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2002
2002
Tyrphostins are a family of tyrosine kinase inhibitors originally synthesized as potential anticarcinogenic compounds. Because… (More)
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2000
Highly Cited
2000
Cytokines of the interleukin 6 (IL-6) family, which activates the signal transducer gp130, are major survival and growth factors… (More)
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1998
Highly Cited
1998
Adhesion of human primary skin fibroblasts and ECV304 endothelial cells to immobilized matrix proteins, beta1 or alphav integrin… (More)
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Highly Cited
1997
Highly Cited
1997
A series of the synthetic protein tyrosine kinase inhibitors known as tyrphostins were studied for their effect on insulin-like… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND The gene Sry acts as a developmental switch, initiating a pathway of gene activity that leads to the differentiation… (More)
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1996
Highly Cited
1996
TRANSDUCTION of a mitogenic signal from the cell membrane to the nucleus involves the adapter proteins SHC and Grb2, which… (More)
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1993
Highly Cited
1993
The HER2 (neu/erb-B2) proto-oncogene codes for a transmembrane receptor with tyrosine kinase activity and with high homology to… (More)
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1991
Highly Cited
1991
We have previously described a novel series of low molecular weight protein tyrosine kinase inhibitors which we named tyrphostins… (More)
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1989
Highly Cited
1989
A novel class of low molecular weight protein tyrosine kinase inhibitors is described. These compounds constitute a systematic… (More)
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Highly Cited
1989
Highly Cited
1989
Synthetic compounds called tyrphostins were examined for their effects on cells which are mitogenically responsive to epidermal… (More)
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