Skip to search formSkip to main contentSkip to account menu

Tyrphostins

Known as: Tyrphostins [Chemical/Ingredient], tyrphostin 
A family of synthetic protein tyrosine kinase inhibitors. They selectively inhibit receptor autophosphorylation and are used to study receptor… 
National Institutes of Health

Related topics

Related topics

38 relations

Narrower (30)

4-nitrobenzylidene malononitrile6,7-dimethoxy-3-phenylquinoxalineAG 127AG 30

Broader (2)

Antineoplastic AgentsEnzyme Inhibitors
In Bloodagonistsantagonists & inhibitorsaspects of radiation effects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2003
2003
Inhibition of Constitutive STAT 3 Activity Sensitizes Resistant Non-Hodgkin ’ s Lymphoma and Multiple Myeloma to Chemotherapeutic Drug-mediated Apoptosis 1
Hematopoietic malignancies have been shown to depend on cytokine growth factor autocrine/paracrine loops for growth and… 
2002
2002
Tyrphostins inhibit lipopolysaccharide induced preterm labor in mice
Abstract Objective: We tested whether lipopolysaccharide (LPS)-induced murine preterm birth was delayed by tyrphostins… 
2002
2002
Involvement of Protein Tyrosine Kinases and Phosphatases in Uptake and Intracellular Replication of Virulent and Avirulent Leishmania donovani Promastigotes in Mouse Macrophage Cells
In this study we show that protein tyrosine kinases (PTKs) and also protein tyrosine phosphatases are involved in the uptake of… 
2001
2001
Induction of I k Ba Degradation and iNOS Expression in a Skin Dendritic Cell Line Is Prevented by the Janus Kinase 2 Inhibitor , Tyrphostin B 42
The Janus kinase (JAK) family of protein tyrosine kinases are activated in response to a wide variety of external stimuli. Here… 
2000
2000
Inhibitory effects of EGFR antisense oligodeox ynucleotide in human colorectal cancer cell line.
Epidermal-growth-factor receptor[1] (EGFR) is a polypeptide with 1186 amino acids, which binds to EGF family growth factors. Two… 
2000
2000
Macrophage protein kinase C: its role in modulating membrane microviscosity and superoxide in leishmanial infection.
Pretreatment of macrophages with, an agonist of PKC, showed diverse effects on degradation and survival of two virulent strains… 
1999
1999
Hydrogen peroxide stimulates tyrosine phosphorylation of focal adhesion kinase in vascular endothelial cells
SURYANARAYANA VEPA,1 WILLIAM M. SCRIBNER,2 NARASIMHAM L. PARINANDI,1 DENIS ENGLISH,3, JOE G. N. GARCIA,1 AND VISWANATHAN… 
1998
1998
Inhibition of Lipopolysaccharide (LPS)-lnduced Endothelial Cytotoxicity by Selected Flavonoids
in vitro 
1998
1998
Effect of tyrosine kinase inhibition on surfactant protein A gene expression during human lung development.
Epidermal growth factor (EGF) stimulates surfactant protein (SP) A synthesis in human fetal lung explants. Ligand binding to the… 
1993
1993
Regulation of IgD-receptor expression on murine T cells. II. Upregulation of IgD receptors is obtained after activation of various intracellular second-messenger systems; tyrosine kinase activity is…
The presence of IgD receptors (IgD-R) on T cells during a primary response to antigen causes augmented antibody production and… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)