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troglitazone

Known as: 5-[[4-[4(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl\-2,4-thiazolidinedione, 5-((4-((3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy)phenyl)methyl)-2,4-Thiazolidinedione, 5-[4-[(6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl)methoxy]benzyl]-2,4-thiazolidinedione 
An orally-active thiazolidinedione with antidiabetic and hepatotoxic properties and potential antineoplastic activity. Troglitazone activates… 
National Institutes of Health

Papers overview

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Review
2003
Review
2003
In 1997, an International Expert Committee was convened to reexamine the classification and diagnostic criteria of diabetes… 
Review
2002
Review
2002
The peroxisome proliferator-activated receptors (PPARs) are a group of three nuclear receptor isoforms, PPAR gamma, PPAR alpha… 
Highly Cited
2001
Highly Cited
2001
We hypothesized that the administration of troglitazone, an insulin-sensitizing agent of the thiazolidinedione class, would… 
Highly Cited
1998
Highly Cited
1998
Troglitazone (CS-045) is one of the thiazolidinediones that activate the peroxisome proliferator-activated receptor gamma… 
Highly Cited
1998
Highly Cited
1998
BACKGROUND Combination therapy is logical for patients with non-insulin-dependent (type 2) diabetes mellitus, because they often… 
Highly Cited
1998
Highly Cited
1998
Troglitazone, a thiazolidinedione derivative, is a widely used antidiabetic drug that binds and activates peroxisome proliferator… 
Highly Cited
1996
Highly Cited
1996
Vascular smooth muscle cell (VSMC) proliferation and migration are responses to arterial injury that are highly important to the… 
Highly Cited
1996
Highly Cited
1996
We performed this study to investigate the hypothesis that insulin resistance plays a role in the pathogenesis of reproductive… 
Highly Cited
1994
Highly Cited
1994
BACKGROUND Troglitazone decreases insulin resistance and hyperglycemia in patients with non-insulin-dependent diabetes mellitus…