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CS 045

Known as: CS-045 
National Institutes of Health

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Related topics

1 relation

Broader (1)

troglitazone

Papers overview

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2006
2006
Effects of Troglitazone (CS-045) on insulin secretion in isolated rat pancreatic islets and HIT cells: an insulinotropic mechanism distinct from glibenclamide
SummaryIn order to elucidate the direct effects of (±)-5-[4-(6-hydroxy-2, 5, 7, 8-tetramethylchroman-2-yl-methoxy) benzyl]-2,4… 
2000
2000
Troglitazone (CS-045) normalizes hypertriglyceridemia and restores the altered patterns of glucose-stimulated insulin secretion in dyslipidemic rats.
Rats fed a sucrose-rich diet ([SRD] 63% wt/wt) up to 270 days develop stable hypertriglyceridemia, impaired glucose tolerance… 
1998
1998
Troglitazone (CS-045) inhibits beta-cell proliferation rate following stimulation of insulin secretion in HIT-T 15 cells.
Thiazolidinedione analogs are new antidiabetic agents that attenuate peripheral insulin resistance in noninsulin-dependent… 
Highly Cited
1997
Highly Cited
1997
Troglitazone (CS-045) ameliorates albuminuria in streptozotocin-induced diabetic rats.
1997
1997
Modulation by serum glucose levels on morphine-induced antinociceptive effect in C57BL/KsJ-db/db mice.
1996
1996
Acute and chronic effects of troglitazone (CS-045) on isolated rat ventricular cardiomyocytes
SummaryFreshly isolated and primary cultured adult rat cardiomyocytes were used to elucidate the mechanism of action of the new… 
Highly Cited
1995
Highly Cited
1995
Regulation of glucose transport in cultured muscle cells by novel hypoglycemic agents.
1994
1994
Evidence against a role of insulin in hypertension in spontaneously hypertensive rats. CS-045 does not lower blood pressure despite improvement of insulin resistance.
Hyperinsulinemia resulting from peripheral insulin resistance has been demonstrated both in spontaneously hypertensive rats (SHR… 
1993
1993
Thiazolidinediones (AD-4833 and CS-045) improve hepatic insulin resistance in streptozotocin-induced diabetic rats.
To investigate whether thiazolidinediones (AD-4833 and CS-045), new oral antidiabetic agents, are effective in insulin-dependent… 
Highly Cited
1991
Highly Cited
1991
A pilot clinical trial of a new oral hypoglycemic agent, CS-045, in patients with non-insulin dependent diabetes mellitus.
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