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trofosfamide

Known as: N,N-3'-tris(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine, 2-oxide, 2-[bis(2-chloroethyl)amino]-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxaphosphorine 2-oxide, N,N,3-tris(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide 
An orally bioavailable oxazaphosphorine prodrug with antineoplastic activity. Trofosfamide (TFF) is metabolized predominantly to the cyclophosphamide… 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2013
Highly Cited
2013
Estrogen receptor (ESR1) drives growth in the majority of human breast cancers by binding to regulatory elements and inducing… 
Highly Cited
2009
Highly Cited
2009
BACKGROUND & AIMS Goblet cells (GC) facilitate mucosal protection and epithelial barrier repair, yet the innate immune mechanisms… 
Review
2008
Review
2008
  • S. Kjellev
  • Cellular and Molecular Life Sciences
  • 2008
  • Corpus ID: 185308
Abstract.The trefoil factor family (TFF) comprises a group of small peptides which are highly expressed in tissues containing… 
Highly Cited
2004
Highly Cited
2004
BACKGROUND & AIMS Effective therapeutics for treating acute colitis, caused by disruption of the intestinal epithelial barrier… 
Review
2003
Review
2003
Recent research has examined Akt and Akt-related serine–threonine kinases in signaling cascades that regulate cell survival and… 
Review
2001
Review
2001
  • A. Dignass, A. Sturm
  • European journal of gastroenterology & hepatology
  • 2001
  • Corpus ID: 38155516
A continuously increasing number of regulatory peptides has been demonstrated to be expressed in the intestine and to modulate… 
Highly Cited
1997
Highly Cited
1997
Conventional tangential flow filtration (TFF) has traditionally been limited to separation of solutes that differ by about ten… 
Highly Cited
1991
Highly Cited
1991
Primer-directed enzyme amplification was used to examine epidermal growth factor (EGF) and transforming growth factor alpha (TGF…