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trofosfamide

Known as: N,N-3'-tris(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine, 2-oxide, 2-[bis(2-chloroethyl)amino]-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxaphosphorine 2-oxide, N,N,3-tris(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide 
An orally bioavailable oxazaphosphorine prodrug with antineoplastic activity. Trofosfamide (TFF) is metabolized predominantly to the cyclophosphamide… 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (4)

Antineoplastic Agents, AlkylatingCyclophosphamideImmunosuppressive AgentsMutagens

Narrower (1)

Ixoten
NCIt Antineoplastic Agent Terminologyanalogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Rapid screening of aquatic toxicity of several metal-based nanoparticles using the MetPLATE™ bioassay.
2012
2012
Traffic Flow Control using Neural Network
With rapid increase in motorization, urbanization, population growth, and changes in population density, Traffic Congestion… 
2010
2010
In vivo action of trefoil factor 2 (TFF2) to speed gastric repair is independent of cyclooxygenase
Objective Trefoil factor (TFF) peptides are expressed in gastric tissues, where they are part of the epithelial defences. To… 
2006
2006
Administered activity and metastatic cure probability during radioimmunotherapy of ovarian cancer in nude mice with 211At-MX35 F(ab')2.
Highly Cited
2004
Highly Cited
2004
Immunoassays of human trefoil factors 1 and 2: measured on serum from patients with inflammatory bowel disease
Background: The trefoil factors (TFF1–3) are cysteine‐rich peptides expressed in the gastrointestinal tract where they play a… 
2004
2004
Investigations on the high molecular weight foaming fractions of espresso coffee.
The target of the present work was the chemical, technological, and sensorial characterization of the brown polymers (foaming… 
1998
1998
5'-flanking motifs control cell-specific expression of trefoil factor genes (TFF).
A group of secreted peptides (trefoil factor family; TFF) is abundantly expressed at mucosal surfaces of the gastrointestinal… 
1998
1998
Life history and the fitness consequences of imperfect information
The acquisition of information incurs costs in time, energy, exposure to predation, and/or lost opportunity. Without information… 
1991
1991
Ocular disease leads to decreased concentrations of epidermal growth factor in the tear fluid.
The concentration of epidermal growth factor (EGF) in tear fluid (TF) was recently shown to decrease with increasing tear fluid… 
1984
1984
Quantification of acrosclerosis: measurement of skin thickness and skin-phalanx distance in females with 15 MHz pulsed ultrasound.
The skin thickness of the extensor and flexor aspects of the forearm (TEF, TFF), and the skin-phalanx distance over the middle… 
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