Ixoten
National Institutes of Health
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SummaryUrotoxic side effects, especially hemorrhagic cystitis, have so far been a limiting factor in the therapeutic use of…
Trofosfamide (Ixoten; Baxter Oncology, Germany) is an alkylating agent that, as with other oxazaphosphorine derivatives, has to…
GOALS OF WORK
There is a need for an effective and nontoxic chemotherapy for palliative indication in non-Hodgkin's lymphoma (NHL…
Comparison of pharmacological properties of commercial, racemic trofosfamide (Ixoten) and its dextrorotatory and levorotatory…
Clinical experience with Ixoten (trofosfamide), a derivative of cyclophosphamide, is reported in 29 patients with malignant…
In an open multicenter phase III trial, prophylaxis of the urinary tract with sodium 2-mercaptoethanesulfonate (Mesnum) was…
The efficacy of trofosfamide (Ixoten; Noristan), a derivative of cyclophosphamide, was investigated in 76 patients. Those with…
Cytostatic therapy under conditions of "partial synchronisation" is reported. 12 patients with extensive metastases of malignant…