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trastuzumab

Known as: Anti-p185-HER2, Anti-HER2/c-erbB2 Monoclonal Antibody, Anti-c-ERB-2 
A monoclonal antibody that binds to HER2 (human epidermal growth factor receptor 2), and can kill HER2-positive cancer cells. Monoclonal antibodies… 
National Institutes of Health

Related topics

Related topics

21 relations

Narrower (3)

ABP 980HerceptinPF-05280014
AC-T-T RegimenAntibody-Dependent Cellular CytotoxicityDrug AllergyERBB2 protein, human

Broader (1)

Antineoplastic Agents

Papers overview

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Highly Cited
1994
Highly Cited
1994
Affinity probe capillary electrophoresis: analysis of recombinant human growth hormone with a fluorescent labeled antibody fragment.
A new highly sensitive microscale analytical procedure called affinity probe capillary electrophoresis (APCE) is presented. One… 
Highly Cited
1992
Highly Cited
1992
A family of beta 7 integrins on human mucosal lymphocytes.
The heterodimeric protein complex recognized by the human mucosal lymphocyte 1 (HML-1) monoclonal antibody is expressed on 95% of… 
Highly Cited
1988
Highly Cited
1988
Location and chemical synthesis of a binding site for HIV-1 on the CD4 protein.
The human immunodeficiency virus type 1 (HIV-1) uses the CD4 protein as a receptor for infection of susceptible cells. A… 
Highly Cited
1987
Highly Cited
1987
Immunochemical proof that a novel rearranging gene encodes the T cell receptor delta subunit.
The T cell receptor (TCR) delta protein is expressed as part of a heterodimer with TCR gamma, in association with the CD3… 
Highly Cited
1984
Highly Cited
1984
T cell-activating properties of an anti-Thy-1 monoclonal antibody. Possible analogy to OKT3/Leu-4
We have identified a single rat monoclonal antibody, G7, that is a potent inducer of interleukin (IL-2) production from all… 
Highly Cited
1984
Highly Cited
1984
Morphologic and phenotypic features of the subpopulation of Leu-2+ cells that suppresses B cell differentiation.
The Leu-2 antigen is expressed on a subpopulation of human T cells that perform suppressor and cytotoxic functions. In addition… 
Highly Cited
1983
Highly Cited
1983
Visualization of lipoprotein receptors by ligand blotting.
Highly Cited
1983
Highly Cited
1983
Characterization of a novel differentiation antigen complex recognize by a monoclonal antibody (A-1A5): unique activation-specific molecular forms on stimulated T cells.
By using a single monoclonal antibody, a novel glycoprotein complex composed of at least three distinct bands was defined on the… 
Highly Cited
1980
Highly Cited
1980
Macrophage heterogeneity in man. A subpopulation of HLA-DR-bearing macrophages required for antigen-induced T cell activation also contains stimulators for autologous-reactive T cells
Utilizing somatic cell hybridization, we have developed a monoclonal antibody that interacts only with cells of the monocyte… 
Highly Cited
1980
Highly Cited
1980
Anti-Thy 1.2 monoclonal antibody linked to ricin is a potent cell-type-specific toxin.
The cell-type specificity of the toxin ricin, which ordinarily binds, enters, and kills cells through receptors containing… 
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