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trastuzumab
Known as:
Anti-p185-HER2
, Anti-HER2/c-erbB2 Monoclonal Antibody
, Anti-c-ERB-2
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A monoclonal antibody that binds to HER2 (human epidermal growth factor receptor 2), and can kill HER2-positive cancer cells. Monoclonal antibodies…
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National Institutes of Health
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Related topics
Related topics
21 relations
Narrower (3)
ABP 980
Herceptin
PF-05280014
AC-T-T Regimen
Antibody-Dependent Cellular Cytotoxicity
Drug Allergy
ERBB2 protein, human
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Broader (1)
Antineoplastic Agents
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1994
Highly Cited
1994
Affinity probe capillary electrophoresis: analysis of recombinant human growth hormone with a fluorescent labeled antibody fragment.
K. Shimura
,
B. Karger
Analytical Chemistry
1994
Corpus ID: 42415897
A new highly sensitive microscale analytical procedure called affinity probe capillary electrophoresis (APCE) is presented. One…
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Highly Cited
1992
Highly Cited
1992
A family of beta 7 integrins on human mucosal lymphocytes.
Christina M. Parker
,
K. L. Cepek
,
+4 authors
M. B. Brenner
Proceedings of the National Academy of Sciences…
1992
Corpus ID: 8889679
The heterodimeric protein complex recognized by the human mucosal lymphocyte 1 (HML-1) monoclonal antibody is expressed on 95% of…
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Highly Cited
1988
Highly Cited
1988
Location and chemical synthesis of a binding site for HIV-1 on the CD4 protein.
Bradford A. Jameson
,
Patricia E. Rao
,
+4 authors
Stephen B. H. Kent
Science
1988
Corpus ID: 37212419
The human immunodeficiency virus type 1 (HIV-1) uses the CD4 protein as a receptor for infection of susceptible cells. A…
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Highly Cited
1987
Highly Cited
1987
Immunochemical proof that a novel rearranging gene encodes the T cell receptor delta subunit.
H. Band
,
F. Hochstenbach
,
J. Mclean
,
S. Hata
,
M. Krangel
,
M. Brenner
Science
1987
Corpus ID: 21028846
The T cell receptor (TCR) delta protein is expressed as part of a heterodimer with TCR gamma, in association with the CD3…
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Highly Cited
1984
Highly Cited
1984
T cell-activating properties of an anti-Thy-1 monoclonal antibody. Possible analogy to OKT3/Leu-4
Kurt C. Gunter
,
Thomas R. Malek
,
E. Shevach
Journal of Experimental Medicine
1984
Corpus ID: 1700853
We have identified a single rat monoclonal antibody, G7, that is a potent inducer of interleukin (IL-2) production from all…
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Highly Cited
1984
Highly Cited
1984
Morphologic and phenotypic features of the subpopulation of Leu-2+ cells that suppresses B cell differentiation.
L. Clement
,
C. Grossi
,
G. Gartland
Journal of Immunology
1984
Corpus ID: 24648828
The Leu-2 antigen is expressed on a subpopulation of human T cells that perform suppressor and cytotoxic functions. In addition…
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Highly Cited
1983
Highly Cited
1983
Visualization of lipoprotein receptors by ligand blotting.
T O Daniel
,
W J Schneider
,
J. L. Goldstein
,
M. Brown
Journal of Biological Chemistry
1983
Corpus ID: 21489276
Highly Cited
1983
Highly Cited
1983
Characterization of a novel differentiation antigen complex recognize by a monoclonal antibody (A-1A5): unique activation-specific molecular forms on stimulated T cells.
M. Hemler
,
C. Ware
,
J. Strominger
Journal of Immunology
1983
Corpus ID: 5681759
By using a single monoclonal antibody, a novel glycoprotein complex composed of at least three distinct bands was defined on the…
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Highly Cited
1980
Highly Cited
1980
Macrophage heterogeneity in man. A subpopulation of HLA-DR-bearing macrophages required for antigen-induced T cell activation also contains stimulators for autologous-reactive T cells
H. Raff
,
L. Picker
,
J. Stobo
Journal of Experimental Medicine
1980
Corpus ID: 7864644
Utilizing somatic cell hybridization, we have developed a monoclonal antibody that interacts only with cells of the monocyte…
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Highly Cited
1980
Highly Cited
1980
Anti-Thy 1.2 monoclonal antibody linked to ricin is a potent cell-type-specific toxin.
R. Youle
,
D. Neville
Proceedings of the National Academy of Sciences…
1980
Corpus ID: 12290939
The cell-type specificity of the toxin ricin, which ordinarily binds, enters, and kills cells through receptors containing…
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