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trastuzumab

Known as: Anti-p185-HER2, Anti-HER2/c-erbB2 Monoclonal Antibody, Anti-c-ERB-2 
A monoclonal antibody that binds to HER2 (human epidermal growth factor receptor 2), and can kill HER2-positive cancer cells. Monoclonal antibodies… 
National Institutes of Health

Related topics

Related topics

21 relations

Narrower (3)

ABP 980HerceptinPF-05280014
AC-T-T RegimenAntibody-Dependent Cellular CytotoxicityDrug AllergyERBB2 protein, human

Broader (1)

Antineoplastic Agents

Papers overview

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Highly Cited
1997
Highly Cited
1997
Chronic alcohol intoxication induces hepatic injury through enhanced macrophage inflammatory protein‐2 production and intercellular adhesion molecule‐1 expression in the liver
This study tested the hypothesis that prolonged consumption of alcohol directly or indirectly, through endotoxin influx in the… 
Highly Cited
1995
Highly Cited
1995
Characterisation of epitopes on human p53 using phage-displayed peptide libraries: insights into antibody-peptide interactions.
We previously described the use of a phage-displayed library of random hexapeptides to define and localise the epitope on the… 
Highly Cited
1994
Highly Cited
1994
Native oligomeric human immunodeficiency virus type 1 envelope glycoprotein elicits diverse monoclonal antibody reactivities
We synthesized and purified a recombinant human immunodeficiency virus type 1 (HIV-1) envelope (Env) glycoprotein, lacking the… 
Highly Cited
1994
Highly Cited
1994
Affinity probe capillary electrophoresis: analysis of recombinant human growth hormone with a fluorescent labeled antibody fragment.
A new highly sensitive microscale analytical procedure called affinity probe capillary electrophoresis (APCE) is presented. One… 
Highly Cited
1992
Highly Cited
1992
A family of beta 7 integrins on human mucosal lymphocytes.
The heterodimeric protein complex recognized by the human mucosal lymphocyte 1 (HML-1) monoclonal antibody is expressed on 95% of… 
Highly Cited
1988
Highly Cited
1988
Genetic analysis of monoclonal antibody and HIV binding sites on the human lymphocyte antigen CD4
Highly Cited
1987
Highly Cited
1987
Immunochemical proof that a novel rearranging gene encodes the T cell receptor delta subunit.
The T cell receptor (TCR) delta protein is expressed as part of a heterodimer with TCR gamma, in association with the CD3… 
Highly Cited
1985
Highly Cited
1985
Reversal of experimental allergic encephalomyelitis with monoclonal antibody to a T-cell subset marker.
Administration of a monoclonal antibody (GK1.5) that recognizes the L3T4 marker present on helper T cells prevented the… 
Highly Cited
1984
Highly Cited
1984
T cell-activating properties of an anti-Thy-1 monoclonal antibody. Possible analogy to OKT3/Leu-4
We have identified a single rat monoclonal antibody, G7, that is a potent inducer of interleukin (IL-2) production from all… 
Highly Cited
1983
Highly Cited
1983
Visualization of lipoprotein receptors by ligand blotting.
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