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tiazofurin

Known as: 2-ribofuranosylthiazole-4-carboxamide, Riboxamide, TCAR 
A synthetic nucleoside analogue with antineoplastic activity. Tiazofurin (TR) is anabolized intracellularly to an analogue of NAD, tiazole-4… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Total chlorophyll (T-Chl), total carotenoids (TCAR) and total phenolics (TPc) compounds were quantified in the biomasses of Ulva… Expand
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Highly Cited
2004
Highly Cited
2004
NAD+ is essential for life in all organisms, both as a coenzyme for oxidoreductases and as a source of ADPribosyl groups used in… Expand
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Highly Cited
2004
Highly Cited
2004
Infections involving Staphylococcus aureus are often more severe and difficult to treat when the organism assumes a biofilm mode… Expand
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Highly Cited
2003
Highly Cited
2003
With the envisioned introduction of three-carrier GNSS’s (modernized GPS, Galileo), new methods of ambiguity resolution have been… Expand
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Highly Cited
1997
Highly Cited
1997
The accuracy requirements of future satellite-based positioning applications are expected to necessitate the use of carrier-phase… Expand
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Highly Cited
1995
Highly Cited
1995
The syntheses of furan and thiophene analogues of tiazofurin (furanfurin and thiophenfurin, respectively) are described. Direct… Expand
Highly Cited
1989
Highly Cited
1989
Tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide, NSC 286193), a selective inhibitor of the activity of IMP dehydrogenase… Expand
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Highly Cited
1989
Highly Cited
1989
Recurrent swelling of the parotid and submandibular salivary glands occurs in some patients with Sjögren's syndrome (SS). Using… Expand
Highly Cited
1985
Highly Cited
1985
The mechanism of the cellular toxicity of four inosinate dehydrogenase (IMP-DH) inhibitors with different antitumor and antiviral… Expand
Highly Cited
1984
Highly Cited
1984
Tiazofurin, a C-nucleoside, was cytotoxic in hepatoma 3924A cells grown in culture with an LC50 = 7.5 microM. In the culture, a… Expand