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Purine Synthesis Inhibition

Purine Synthesis Inhibition involves interference with, or restraint of, the activities of biologic molecules or complexes involved in the enzymatic… 
National Institutes of Health

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5 relations
Thioguanineedatrexatemercaptopurinetalotrexin

Papers overview

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2003
2003
A Defect in the p53 Response Pathway Induced by de Novo Purine Synthesis Inhibition*
p53 is believed to sense cellular ribonucleotide depletion in the absence of DNA strand breaks and to respond by imposition of a… 
1994
1994
Enhancement of antineoplastic activity of 5-fluorouracil in mice bearing colon 38 tumor by (6R)5,10-dideazatetrahydrofolic acid.
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