talotrexin

An antimetabolite analogue of aminopterin with potential antineoplastic activity. As a folate antagonist, talotrexin binds to and inhibits the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2006-2016
0120062016

Papers overview

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2016
2016
Abstract Talotrexin is an antifolate drug with promising antitumor activity. The present study deals with the photodegradation of… (More)
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2009
2009
Renewed interest in antifols for the treatment of childhood cancers has resulted from identification of novel antifols with broad… (More)
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Review
2007
Review
2007
Acute lymphocytic leukemia (ALL) is a heterogeneous group of disorders that are associated with a cure rate of > 80% in children… (More)
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Review
2007
Review
2007
Acute lymphocytic leukaemia (ALL) is a heterogeneous group of disorders that result from the clonal proliferation and expansion… (More)
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2006
2006
7142 Background: Talotrexin is a nonpolyglutamatable antifolate which has demonstrated improved antitumor activity in a broad… (More)
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