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tiagabine

Known as: Tiagabinum, tiagabine [Chemical/Ingredient], Tiagabina 
National Institutes of Health

Related topics

Related topics

15 relations

Broader (4)

AnticonvulsantsGABA AgonistsNeurotransmitter Uptake InhibitorsNipecotic Acids
Antiepileptic AgentsBipolar DisorderDrug AllergyEpilepsies, Partial

Narrower (4)

GabitrilNO 328NO 329Tiagabine hydrochloride

Papers overview

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2011
2011
Analyte and internal standard cross signal contributions and their impact on quantitation in LC-MS based bioanalysis.
2006
2006
Open-label tiagabine monotherapy for major depressive disorder with anxiety.
OBJECTIVE Gamma-aminobutyric acid (GABA) plays a key role in the pathophysiology and treatment of depression and anxiety… 
2004
2004
Acute Vigabatrin Retinotoxicity in Albino Rats Depends on Light But Not GABA
Summary:  Purpose: Vigabatrin (VGB) is an irreversible inhibitor of γ‐aminobutyric acid (GABA) transaminase. Its use as an… 
Review
2004
Review
2004
Mood effects of antiepileptic drugs
2004
2004
Effects of antiepileptic drugs on working memory as assessed by spatial alternation performance in rats
2003
2003
Interlaboratory Variability in the Quantification of New Generation Antiepileptic Drugs Based on External Quality Assessment Data
Summary:  Purpose: To assess interlaboratory variability in the determination of serum levels of new antiepileptic drugs (AEDs). 
Highly Cited
1998
Highly Cited
1998
Effect of the GABA uptake inhibitor tiagabine on sleep and EEG power spectra in the rat
The sleep profiles induced by agonists and agonistic modulators of γ‐aminobutyric acidA (GABAA) receptors differ markedly. With… 
Highly Cited
1997
Highly Cited
1997
Cognitive and quality of life effects of differing dosages of tiagabine in epilepsy
Tiagabine blocks the uptake by neurons or glia of synaptically released GABA resulting in prolonged GABAergic activity and… 
Highly Cited
1995
Highly Cited
1995
International Experience with Tiagabine Add‐On Therapy
Summary: Tiagabine (TGB) hydrochloride is a novel antiepileptic drug (AED) that is a potent and specific inhibitor of… 
Highly Cited
1994
Highly Cited
1994
Rat substantia nigra pars reticulata neurones are tonically inhibited via GABA A, but not GABA B, receptors in vitro
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