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thymidine metabolic process
Known as:
deoxyribosylthymine metabolic process
, deoxyribosylthymine metabolism
, thymidine metabolism
The chemical reactions and pathways involving thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but…
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Changes in Tumor Metabolism as Readout for Mammalian Target of Rapamycin Kinase Inhibition by Rapamycin in Glioblastoma
L. Wei
,
H. Su
,
I. Hildebrandt
,
M. Phelps
,
J. Czernin
,
W. Weber
Clinical Cancer Research
2008
Corpus ID: 17131307
Purpose: Inhibition of the protein kinase mammalian target of rapamycin (mTOR) is being evaluated for treatment of a variety of…
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Highly Cited
2002
Highly Cited
2002
Altered Thymidine Metabolism Due to Defects of Thymidine Phosphorylase*
A. Spinazzola
,
R. Martí
,
+8 authors
M. Hirano
Journal of Biological Chemistry
2002
Corpus ID: 20889950
Mitochondrialneurogastrointestinalencephalomyopathy (MNGIE) is an autosomal recessive human disease due to mutations in the…
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Review
2001
Review
2001
Thymidine phosphorylase: a two-face Janus in anticancer chemotherapy.
F. Focher
,
Silvio Spadari
Current Cancer Drug Targets
2001
Corpus ID: 24355287
Several cytokines and growth factors modulate angiogenesis through a fine tuned paracrine or autocrine mode of action. Among them…
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2000
2000
Novel nonsubstrate inhibitors of human thymidine phosphorylase, a potential target for tumor-dependent angiogenesis.
F. Focher
,
D. Ubiali
,
+4 authors
S. Spadari
Journal of Medicinal Chemistry
2000
Corpus ID: 7945655
Thymidine phosphorylase/platelet-derived endothelial cell growth factor (TP/PD-ECGF) is an enzyme involved in thymidine…
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1992
1992
Metabolism of 4'-azidothymidine. A compound with potent and selective activity against the human immunodeficiency virus.
M. S. Chen
,
R. Suttmann
,
J. Wu
,
E. J. Prisbe
Journal of Biological Chemistry
1992
Corpus ID: 26359405
Highly Cited
1988
Highly Cited
1988
Limitations of the [3H]thymidine method for estimating bacterial productivity due to thymidine metabolism
J. Hollibaugh
1988
Corpus ID: 62877606
Highly Cited
1982
Highly Cited
1982
Purine and pyrimidine salvage pathways in Leishmania donovani.
S. Lafon
,
D. Nelson
,
R. L. Berens
,
J. Marr
Biochemical Pharmacology
1982
Corpus ID: 5547604
Highly Cited
1978
Highly Cited
1978
The relationship of thymidine metabolism to the use of fractional incorporation as a measure of DNA synthesis and tissue proliferation.
K. Tew
,
D. Taylor
European Journal of Cancer
1978
Corpus ID: 26785532
Highly Cited
1977
Highly Cited
1977
Biochemical strategy of the genome as expressed in regulation of pyrimidine metabolism.
G. Weber
,
T. Shiotani
,
H. Kizaki
,
D. Tzeng
,
J. Williams
,
N. Gladstone
Advances in Enzyme Regulation
1977
Corpus ID: 44849995
Highly Cited
1970
Highly Cited
1970
Control of gene expression in carbohydrate, pyrimidine and DNA metabolism.
G. Weber
,
S. Queener
,
J. Ferdinandus
Advances in Enzyme Regulation
1970
Corpus ID: 43909754
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