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telithromycin

Known as: (1S,2R,5R,7R,8R,9S,11R,13R,14R)-8-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-15-[4-(4-pyridin-3-ylimidazol-1-yl)butyl]-3,17-dioxa-15-azabicyclo[12.3.0]heptadecane-4,6,12,16-tetrone, telithromycin [Chemical/Ingredient] 
National Institutes of Health

Related topics

Related topics

10 relations

Broader (1)

Anti-Bacterial Agents
Bacterial InfectionsDecreased Protein Synthesis [PE]KetolidesProtein Synthesis Inhibitors [MoA]

Narrower (3)

HMR 3647KetekRU 66647

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Differences in assessment of macrolide interaction with human MDR1 (ABCB1, P-gp) using rhodamine-123 efflux, ATPase activity and cellular accumulation assays.
2008
2008
Macrolide-lincosamide-streptogramin B resistance phenotypes in clinical staphylococcal isolates.
2006
2006
Myasthenia gravis exacerbation or unmasking associated with telithromycin treatment
Telithromycin, a new ketolide antibiotic, has been implicated in the exacerbation or unmasking of myasthenia gravis. This… 
Highly Cited
2006
Highly Cited
2006
Resistance to Erythromycin and Telithromycin in Streptococcus pyogenes Isolates Obtained between 1999 and 2002 from Greek Children with Tonsillopharyngitis: Phenotypic and Genotypic Analysis
ABSTRACT Since the late 1990s, the prevalence of erythromycin-resistant Streptococcus pyogenes has significantly increased in… 
Highly Cited
2002
Highly Cited
2002
Comparison of In Vitro Activities of ABT-773 and Telithromycin against Macrolide-Susceptible and -Resistant Streptococci and Staphylococci
ABSTRACT The activity of a new ketolide, ABT-773, was compared to the activity of the ketolide telithromycin (HMR-3647) against… 
Highly Cited
2001
Highly Cited
2001
Lung concentrations of telithromycin after oral dosing.
Concentrations of telithromycin were measured in plasma, bronchial mucosa (BM), epithelial lining fluid (ELF) and alveolar… 
2001
2001
Telithromycin. Author's Reply
Telithromycin is the first member of a new family of the macrolide-lincosamide-streptogramin-B (MLS B ) class of antimicrobials… 
Highly Cited
2000
Highly Cited
2000
In Vitro Development of Resistance to Telithromycin (HMR 3647), Four Macrolides, Clindamycin, and Pristinamycin inStreptococcus pneumoniae
ABSTRACT The ability of 50 sequential subcultures in subinhibitory concentrations of telithromycin (HMR 3647), azithromycin… 
Highly Cited
2000
Highly Cited
2000
Comparative Activities of Telithromycin (HMR 3647), Levofloxacin, and Other Antimicrobial Agents against Human Mycoplasmas
ABSTRACT The activities of telithromycin and levofloxacin against 99 mycoplasma strains were compared to those of several… 
2000
2000
Antipneumococcal Activity of Telithromycin by Agar Dilution, Microdilution, E Test, and Disk Diffusion Methodologies
ABSTRACT Agar dilution and microdilution (both in air) and E test and disk diffusion (both in air and CO2) were used to test the… 
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