telithromycin

Known as: (1S,2R,5R,7R,8R,9S,11R,13R,14R)-8-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-15-[4-(4-pyridin-3-ylimidazol-1-yl)butyl]-3,17-dioxa-15-azabicyclo[12.3.0]heptadecane-4,6,12,16-tetrone, telithromycin [Chemical/Ingredient] 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2017
05010019992017

Papers overview

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Highly Cited
2010
Highly Cited
2010
Differences between the structures of bacterial, archaeal, and eukaryotic ribosomes account for the selective action of… (More)
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Highly Cited
2009
Highly Cited
2009
Mycobacterium abscessus infections tend to respond poorly to macrolide-based chemotherapy, even though the organisms appear to be… (More)
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Highly Cited
2008
Highly Cited
2008
Drug-induced liver injury (DILI) is the most common adverse event causing drug nonapprovals and drug withdrawals. Using drugs as… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND We conducted a double-blind, randomized, placebo-controlled study to evaluate the efficacy of telithromycin in… (More)
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2005
2005
Macrolide antibiotics have an outstanding ability to concentrate within host cells, particularly phagocytes. In the study… (More)
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Highly Cited
2005
Highly Cited
2005
Crystal structures of H. marismortui large ribosomal subunits containing the mutation G2099A (A2058 in E. coli) with erythromycin… (More)
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Highly Cited
2003
Highly Cited
2003
The macrolide-lincosamide-streptogramin B class (MLS) of antibiotics contains structurally different but functionally similar… (More)
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Highly Cited
2002
Highly Cited
2002
Mechanisms of resistance were studied in 22 macrolide-resistant mutants selected in vitro from 5 parental strains of macrolide… (More)
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Highly Cited
2002
Highly Cited
2002
The prevalence of resistance to a range of antimicrobials was determined for isolates of Streptococcus pneumoniae examined in the… (More)
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2001
2001
Concentrations of telithromycin were measured in plasma, bronchial mucosa (BM), epithelial lining fluid (ELF) and alveolar… (More)
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