Skip to search formSkip to main contentSkip to account menu

telithromycin

Known as: (1S,2R,5R,7R,8R,9S,11R,13R,14R)-8-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyl-oxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-15-[4-(4-pyridin-3-ylimidazol-1-yl)butyl]-3,17-dioxa-15-azabicyclo[12.3.0]heptadecane-4,6,12,16-tetrone, telithromycin [Chemical/Ingredient] 
National Institutes of Health

Related topics

Related topics

10 relations

Broader (1)

Anti-Bacterial Agents
Bacterial InfectionsDecreased Protein Synthesis [PE]KetolidesProtein Synthesis Inhibitors [MoA]

Narrower (3)

HMR 3647KetekRU 66647

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Differences in assessment of macrolide interaction with human MDR1 (ABCB1, P-gp) using rhodamine-123 efflux, ATPase activity and cellular accumulation assays.
Highly Cited
2006
Highly Cited
2006
Resistance to Erythromycin and Telithromycin in Streptococcus pyogenes Isolates Obtained between 1999 and 2002 from Greek Children with Tonsillopharyngitis: Phenotypic and Genotypic Analysis
ABSTRACT Since the late 1990s, the prevalence of erythromycin-resistant Streptococcus pyogenes has significantly increased in… 
2006
2006
Myasthenia gravis exacerbation or unmasking associated with telithromycin treatment
Telithromycin, a new ketolide antibiotic, has been implicated in the exacerbation or unmasking of myasthenia gravis. This… 
Review
2004
Review
2004
Tissue kinetics of telithromycin, the first ketolide antibacterial.
The potential efficacy of an antibacterial depends not only on its spectrum of activity but also on its concentration at the site… 
2003
2003
A Comparison of the Efficacy of Telithromycin versus Cefuroxime Axetil in the Treatment of Acute Bacterial Maxillary Sinusitis
Background Telithromycin, a new ketolide, exhibits potent activity against respiratory pathogens, including resistant strains… 
Highly Cited
2001
Highly Cited
2001
Lung concentrations of telithromycin after oral dosing.
Concentrations of telithromycin were measured in plasma, bronchial mucosa (BM), epithelial lining fluid (ELF) and alveolar… 
2001
2001
Telithromycin. Author's Reply
Telithromycin is the first member of a new family of the macrolide-lincosamide-streptogramin-B (MLS B ) class of antimicrobials… 
Highly Cited
2000
Highly Cited
2000
In Vitro Development of Resistance to Telithromycin (HMR 3647), Four Macrolides, Clindamycin, and Pristinamycin inStreptococcus pneumoniae
ABSTRACT The ability of 50 sequential subcultures in subinhibitory concentrations of telithromycin (HMR 3647), azithromycin… 
2000
2000
Antipneumococcal Activity of Telithromycin by Agar Dilution, Microdilution, E Test, and Disk Diffusion Methodologies
ABSTRACT Agar dilution and microdilution (both in air) and E test and disk diffusion (both in air and CO2) were used to test the… 
1999
1999
Activities of Telithromycin (HMR 3647, RU 66647) Compared to Those of Erythromycin, Azithromycin, Clarithromycin, Roxithromycin, and Other Antimicrobial Agents against Unusual Anaerobes
ABSTRACT The comparative activity of telithromycin (HMR 3647) against 419 human anaerobic isolates was determined by the agar… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)