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HMR 3647

Known as: HMR-3647, HMR3647 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

telithromycin

Papers overview

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2002
2002
Osmolytes stimulate the reconstitution of functional 50S ribosomes from in vitro transcripts of Escherichia coli 23S rRNA.
Functional Escherichia coli 50S ribosomal subunits can be reconstituted from their natural rRNA and protein components. However… 
2002
2002
Telithromycin Inhibition of Protein Synthesis and 50S Ribosomal Subunit Formation in Streptococcus pneumoniae Cells
The new ketolide antibiotic telithromycin (HMR3647) has been examined for inhibitory effects in cells of Streptococcus pneumoniae… 
Highly Cited
2002
Highly Cited
2002
Comparison of In Vitro Activities of ABT-773 and Telithromycin against Macrolide-Susceptible and -Resistant Streptococci and Staphylococci
ABSTRACT The activity of a new ketolide, ABT-773, was compared to the activity of the ketolide telithromycin (HMR-3647) against… 
Review
2001
Review
2001
Recent developments on ketolides and macrolides.
Recent semi-synthetic studies of erythromycin A culminated in the discovery of two ketolide drug candidates, HMR-3647 and ABT-773… 
2001
2001
In Vivo Efficacy of Telithromycin (HMR3647) againstStreptococcus pneumoniae and Haemophilus influenzae
ABSTRACT The in vivo activity of telithromycin against erythromycin A- and penicillin G-resistant Streptococcus pneumoniae was… 
2000
2000
In Vitro Activity of Telithromycin (HMR3647), a New Ketolide, against Clinical Isolates of Mycoplasma pneumoniaein Japan
ABSTRACT The in vitro activity of telithromycin (HMR3647), a new ketolide, against Mycoplasma pneumoniae was determined by the… 
Highly Cited
1999
Highly Cited
1999
In Vitro Activities of Ketolide HMR3647, Macrolides, and Other Antibiotics against Lactobacillus,Leuconostoc, and PediococcusIsolates
ABSTRACT Testing of susceptibility to 13 antibiotics was performed with 90 isolates of Lactobacillus, Leuconostoc, andPediococcus… 
Highly Cited
1999
Highly Cited
1999
In Vitro Activity of the Ketolide HMR 3647 (RU 6647) for Legionella spp., Its Pharmacokinetics in Guinea Pigs, and Use of the Drug To Treat Guinea Pigs withLegionella pneumophila Pneumonia
ABSTRACT The activities of HMR 3647, HMR 3004, erythromycin, clarithromycin, and levofloxacin for 97 Legionella spp. isolates… 
Highly Cited
1999
Highly Cited
1999
The New Ketolide HMR3647 Accumulates in the Azurophil Granules of Human Polymorphonuclear Cells
ABSTRACT HMR3647 is a semisynthetic representative of a new group of drugs, the ketolides, derived from erythromycin A. Since… 
1998
1998
Pharmacodynamic properties of HMR 3647, a novel ketolide, on respiratory pathogens, enterococci and Bacteroides fragilis demonstrated by studies of time-kill kinetics and postantibiotic effect.
The pharmacodynamic properties of a novel ketolide (a new class of macrolide), HMR 3647, were investigated by studying time-kill… 
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