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Comparative Genomics of Listeria Species
A large number of predicted genes encoding surface and secreted proteins, transporters, and transcriptional regulators are found, consistent with the ability of both species to adapt to diverse environments.
Antibiotics and antibiotic resistance in water environments.
High frequency of hypermutable Pseudomonas aeruginosa in cystic fibrosis lung infection.
Determination of spontaneous mutation rates in 128 P. aeruginosa isolates from 30 CF patients revealed that 36% of the patients were colonized by a hypermutable (mutator) strain that persisted for years in most patients, revealing a link between high mutations rates in vivo and the evolution of antibiotic resistance.
Increasing prevalence of ESBL-producing Enterobacteriaceae in Europe.
- T. Coque, F. Baquero, R. Cantón
- Biology, MedicineEuro surveillance : bulletin Europeen sur les…
- 20 November 2008
The emergence of epidemic clones harbouring several beta-lactamases simultaneously (ESBLs, metallo-beta-lacticamases or cephamycinases) and of new mechanisms of resistance to fluoroquinolones and aminoglycosides warrants future surveillance studies.
Prevalence and spread of extended-spectrum beta-lactamase-producing Enterobacteriaceae in Europe.
Extended-spectrum beta-lactamases (ESBLs) represent a major threat among resistant bacterial isolates. The first types described were derivatives of the TEM-1, TEM-2 and SHV-1 enzymes during the…
Global Spread of Vancomycin-resistant Enterococcus faecium from Distinct Nosocomial Genetic Complex
Preventing further spread of this epidemic E. faecium subpopulation is critical, and efforts should focus on the early disclosure of ampicillin-resistant complex-17 strains.
Dissemination of Clonally Related Escherichia coli Strains Expressing Extended-Spectrum β-Lactamase CTX-M-15
E. coli ST131 and ST405 and multidrug-resistant IncFII plasmids may determine spread of this lactamase.
Antibiotic Resistance in CampylobacterStrains Isolated from Animals, Foods, and Humans in Spain in 1997–1998
- Y. Sáenz, M. Zarazaga, M. Lantero, M. J. Gastañares, F. Baquero, C. Torres
- Medicine, BiologyAntimicrobial Agents and Chemotherapy
- 1 February 2000
The increasing rates of Campylobacter resistance make advisable a more conservative policy for the use of antibiotics in farm animals.
Tackling antibiotic resistance: the environmental framework
The main knowledge gaps, the future research needs and the policy and management options that should be prioritized to tackle antibiotic resistance in the environment are discussed.
Antibiotics as intermicrobial signaling agents instead of weapons
- J. Linares, I. Gustafsson, F. Baquero, J. Martínez
- BiologyProceedings of the National Academy of Sciences
- 19 December 2006
The results support the notion that antibiotics are not only bacterial weapons for fighting competitors but also signaling molecules that may regulate the homeostasis of microbial communities at low concentrations.