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Ketolides

Known as: 3-Keto Erythromycins, Erythromycins, 3-Keto, 3-Keto-Erythromycins 
Compounds based on ERYTHROMYCIN with the 3-cladinose replaced by a ketone. They bind the 23S part of 70S bacterial RIBOSOMES.
National Institutes of Health

Papers overview

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Review
2019
Review
2012
Review
2012
The first macrolide, erythromycin A, demonstrated broad-spectrum antimicrobial activity and was used primarily for respiratory… 
Review
2007
Review
2007
SUMMARY Haemophilus influenzae is a major community-acquired pathogen causing significant morbidity and mortality worldwide… 
Highly Cited
2001
Highly Cited
2001
ABSTRACT A total of 1,531 recent clinical isolates of Streptococcus pneumoniae were collected from 33 medical centers nationwide… 
Review
2001
Review
2001
Besides their role as commensals on the skin and mucosal surfaces, staphylococci may be involved in a wide variety of diseases in… 
Highly Cited
1999
Highly Cited
1999
Ketolides represent a new generation of macrolide antibiotics. In order to identify the ketolide‐binding site on the ribosome, a… 
Highly Cited
1997
Highly Cited
1997
Ketolides belong to a new class of semi-synthetic 14-membered-ring macrolides, which differ from erythromycin A by having a 3…