Ketolides

Known as: 3-Keto Erythromycins, Erythromycins, 3-Keto, 3-Keto-Erythromycins 
Compounds based on ERYTHROMYCIN with the 3-cladinose replaced by a ketone. They bind the 23S part of 70S bacterial RIBOSOMES.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
024619972017

Papers overview

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2009
2009
Ketolides represent the latest generation of macrolide antibiotics, displaying improved activities against some erythromycin… (More)
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2008
2008
BACKGROUND Despite increasingly frequent bacterial resistance to antibiotics, antibacterial innovation is rare. Ketolides… (More)
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2008
2008
Ketolides, which represent the newest macrolide antibiotics, are generally perceived to be noninducers of inducible erm genes. In… (More)
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2005
2005
Ketolides represent the latest group of macrolide antibiotics. Tight binding of ketolides to the ribosome appears to correlate… (More)
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2004
2004
Ketolides are the latest derivatives developed from the macrolide erythromycin to improve antimicrobial activity. All macrolides… (More)
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2002
2002
Burgeoning resistance to antibiotics among common respiratory pathogens poses a very real risk to public health. A need therefore… (More)
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1999
1999
Ketolides represent a new generation of macrolide antibiotics. In order to identify the ketolide-binding site on the ribosome, a… (More)
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1997
1997
Ketolides belong to a new class of semi-synthetic 14-membered-ring macrolides, which differ from erythromycin A by having a 3… (More)
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1997
1997
Ketolides, a novel macrolide subclass, possess a mode of action that is similar to that of structurally related macrolide… (More)
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1997
1997
Ketolides are a new class of macrolide antibiotics that have been shown to be active against a variety of bacteria including… (More)
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