Skip to search formSkip to main contentSkip to account menu

Ketolides

Known as: 3-Keto Erythromycins, Erythromycins, 3-Keto, 3-Keto-Erythromycins 
Compounds based on ERYTHROMYCIN with the 3-cladinose replaced by a ketone. They bind the 23S part of 70S bacterial RIBOSOMES.
National Institutes of Health

Related topics

Related topics

15 relations

Narrower (8)

3-deoxy-3-oxo-erythronolide BJNJ 17155437JNJ 17155528RU 64004
In BloodKetolide Antibacterial [EPC]agonistsantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Azithromycin, clarithromycin and telithromycin inhibit MUC5AC induction by Chlamydophila pneumoniae in airway epithelial cells.
Highly Cited
2005
Highly Cited
2005
Cellular Uptake and Efflux of Azithromycin, Erythromycin, Clarithromycin, Telithromycin, and Cethromycin
ABSTRACT Macrolide antibiotics have an outstanding ability to concentrate within host cells, particularly phagocytes. In the… 
2004
2004
Pneumococcal resistance to macrolides, lincosamides, ketolides, and streptogramin B agents: molecular mechanisms and resistance phenotypes.
The macrolides, lincosamides, ketolides, and streptogramin B agents (the MLKS(B) antimicrobial agents) have related chemical… 
2003
2003
In vitro activity of linezolid against Clostridium difficile.
Review
2001
Review
2001
Recent developments on ketolides and macrolides.
Recent semi-synthetic studies of erythromycin A culminated in the discovery of two ketolide drug candidates, HMR-3647 and ABT-773… 
Highly Cited
2001
Highly Cited
2001
Bronchopulmonary Disposition of the Ketolide Telithromycin (HMR 3647)
ABSTRACT Telithromycin (HMR 3647) is the first member of a new family of antimicrobials, the ketolides, developed specifically… 
Review
1999
Review
1999
New research in macrolides and ketolides since 1997.
Macrolide and ketolide antibacterials remain a very dynamically active group. To overcome erythromycin A resistance within Gram… 
Review
1999
Review
1999
Therapy for pneumococcal infection at the millennium: doubts and certainties.
Highly Cited
1998
Highly Cited
1998
In Vitro Activities of the New Ketolide Antibiotics HMR 3004 and HMR 3647 against Streptococcus pneumoniae in Germany
ABSTRACT The comparative in vitro activity of HMR 3004 and HMR 3647, new ketolide antibiotics, was tested by a standard agar… 
1997
1997
In-vitro activity of ketolides against mycoplasmas.
than those of TEM-1 for all the -lactams except cefoper azone (Table). K i values of clavulanic acid, sulbactam and tazobactam… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)