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synaptotagmin II

Known as: Synaptotagmin 2, Synaptotagmin II [Chemical/Ingredient] 
A vesicular transport protein that was originally characterized as an inositol polyphosphate binding protein. Synaptotagmin II helps regulate… 
National Institutes of Health

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In BloodProcess of secretionSYT2 geneagonists

Papers overview

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2011
2011
Gβγ and the C Terminus of SNAP-25 Are Necessary for Long-Term Depression of Transmitter Release
Background Short-term presynaptic inhibition mediated by G protein-coupled receptors involves a direct interaction between G… 
2007
2007
Botulinum neurotoxin B–host receptor recognition: it takes two receptors to tango
Two independent crystal structure analyses have resolved the detailed interactions between botulinum neurotoxin serotype B and… 
2006
2006
Structural biology: Dangerous liaisons on neurons
Crystal structures show that botulinum toxins bind simultaneously to two sites on neurons. This dual interaction allows them to… 
2006
2006
Synaptotagmin II immunoreactivity in normal and botulinum type-A treated mouse motor nerve terminals
The distribution of synaptotagmin II, a synaptic vesicle protein, was examined by immunohistochemistry at normai mouse motor… 
2004
2004
Cloning, high-level expression, single-step purification, and binding activity of His6-tagged recombinant type B botulinum neurotoxin heavy chain transmembrane and binding domain.
2002
2002
Suppression of Synaptotagmin II restrains phorbolester-induced downregulation of protein kinase Calpha by diverting the kinase from a degradative pathway to the recycling endocytic compartment.
Downregulation of protein kinase Calpha (PKCalpha) following long-term exposure to phorbol esters such as TPA is traffic… 
2000
2000
Genomic structures of synaptotagmin II protein: comparison of exon-intron organization of the synaptotagmin gene family.
Synaptotagmin (Syt) I (or II) is thought to be a Ca(2+) sensor for neurotransmitter release in the rostral (or caudal) region of… 
1997
1997
Expression of synaptic membrane proteins in gerbil pinealocytes in primary culture
Pinealocytes of various mammalian species contain abundant synaptic‐like microvesicles (SLMVs) which are considered the endocrine… 
1996
1996
Synaptotagmin I, synaptobrevin II, and syntaxin I are coexpressed in rat and gerbil pinealocytes
Abstract.Recent studies have shown that mammalian pinealocytes contain a compartment of synaptic-like microvesicles that may… 
Highly Cited
1994
Highly Cited
1994
Synaptotagmin is an inositol polyphosphate binding protein: isolation and characterization as an Ins 1,3,4,5-P4 binding protein.
We isolated a binding protein for inositol 1,3,4,5-tetrakisphosphate (InsP4) from detergent-solubilized mouse cerebellar membrane… 
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