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synaptotagmin II

Known as: Synaptotagmin 2, Synaptotagmin II [Chemical/Ingredient] 
A vesicular transport protein that was originally characterized as an inositol polyphosphate binding protein. Synaptotagmin II helps regulate… 
National Institutes of Health

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In BloodProcess of secretionSYT2 geneagonists

Papers overview

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2016
2016
N-terminal domain of complexin independently activates calcium-triggered fusion
Significance Synaptic neurotransmitter release is an essential process for communication between neurons. Neurotransmitter… 
Highly Cited
2005
Highly Cited
2005
Membrane-bound orientation and position of the synaptotagmin C2B domain determined by site-directed spin labeling.
Site-directed spin labeling is used to determine the orientation and depth of insertion of the second C2 domain from… 
Highly Cited
2002
Highly Cited
2002
Calcium-independent stimulation of membrane fusion and SNAREpin formation by synaptotagmin I
Ñeurotransmitter release requires the direct coupling of the calcium sensor with the machinery for membrane fusion. SNARE… 
Highly Cited
2001
Highly Cited
2001
Direct Interaction of the Rab3 Effector RIM with Ca2+Channels, SNAP-25, and Synaptotagmin*
To define the role of the Rab3-interacting molecule RIM in exocytosis we searched for additional binding partners of the protein… 
Highly Cited
2001
Highly Cited
2001
Synaptotagmin I is a molecular target for lead
Lead poisoning can cause a wide range of symptoms with particularly severe clinical effects on the CNS. Lead can increase… 
Highly Cited
1998
Highly Cited
1998
Mechanism of phospholipid binding by the C2A-domain of synaptotagmin I.
Synaptotagmin I is a synaptic vesicle membrane protein that probably functions as a Ca2+ sensor in neurotransmitter release and… 
Highly Cited
1998
Highly Cited
1998
Characterization of Clostridium botulinum Type B Neurotoxin Associated with Infant Botulism in Japan
ABSTRACT The neurotoxin of strain 111 (111/NT) associated with type B infant botulism showed antigenic and biological properties… 
Highly Cited
1997
Highly Cited
1997
The first C2 domain of synaptotagmin is required for exocytosis of insulin from pancreatic β‐cells: action of synaptotagmin at low micromolar calcium
The Ca2+‐ and phospholipid‐binding protein synaptotagmin is involved in neuroexocytosis. Its precise role and Ca2+‐affinity in… 
Highly Cited
1995
Highly Cited
1995
Calcium-dependent transmitter secretion from fibroblasts: Modulation by synaptotagmin I
Highly Cited
1994
Highly Cited
1994
Synaptotagmin I is a high affinity receptor for clathrin AP-2: Implications for membrane recycling
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