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- Bin-Zhi Qian, Jiufeng Li, +6 authors Jeffrey W Pollard
- Nature
- 2011
Macrophages, which are abundant in the tumour microenvironment, enhance malignancy. At metastatic sites, a distinct population of metastasis-associated macrophages promotes the extravasation, seeding… (More)
- Yue Xiong, Gregory J Hannon, Hui Zhang, David J. Casso, Ryuji Kobayashi, David S. Beach
- Nature
- 1993
DEREGULATION of cell proliferation is a hallmark of neoplastic transformation. Alteration in growth control pathways must translate into changes in the cell-cycle regulatory machinery, but the… (More)
- Dunyaporn Trachootham, Yan Zhou, +8 authors Peng Huang
- Cancer cell
- 2006
Reactive oxygen species (ROS) stimulate cell proliferation and induce genetic instability, and their increase in cancer cells is often viewed as an adverse event. Here, we show that such abnormal… (More)
- Hui Zhang, Bin Yang, Roger J. Pomerantz, Chune Zhang, Shyamala C. Arunachalam, Ling Gao
- Nature
- 2003
High mutation frequency during reverse transcription has a principal role in the genetic variation of primate lentiviral populations. It is the main driving force for the generation of drug… (More)
- Eduardo Gascon, Laszlo Vutskits, +4 authors Jozsef Z. Kiss
- The European journal of neuroscience
- 2005
Dendritic arbor development of subventricular zone-derived interneurons is a critical step in their integration into functional circuits of the postnatal olfactory bulb. However, the mechanism and… (More)
- Anne M. Fagan, Hui Zhang, Steve Landis, Richard J Smeyne, Inmaculada Silos-Santiago, Mariano Barbacid
- The Journal of neuroscience : the official…
- 1996
Neurotrophins and their signaling receptors, the Trk family of protein tyrosine kinases, play a major role in the development of the mammalian nervous system. To determine the precise stages that… (More)
- Hui Zhang, Geethanjali Dornadula, +4 authors Roger J. Pomerantz
- The New England journal of medicine
- 1998
BACKGROUND
Highly active antiretroviral therapy can effectively decrease the levels of human immunodeficiency virus type 1 (HIV-1) virions in peripheral plasma and seminal fluid of infected men.… (More)
- Austin T Thiel, Peter Blessington, +8 authors Xianxin Hua
- Cancer cell
- 2010
Oncogenic fusion proteins are capable of initiating tumorigenesis, but the role of their wild-type counterparts in this process is poorly understood. The mixed lineage leukemia (MLL) gene undergoes… (More)
- Bin Yang, Keyang Chen, Chune Zhang, Sophia S. Huang, Hui Zhang
- The Journal of biological chemistry
- 2007
Cellular cytidine deaminases APOBEC3 family is a group of potent inhibitors for many exogenous and endogenous retroviruses. It has been demonstrated that they induce G to A hypermutations in the… (More)
- Nikolai G Kholodilov, Olga Yarygina, +4 authors Robert E Burke
- The Journal of neuroscience : the official…
- 2004
Glial cell line-derived neurotrophic factor (GDNF) has been shown to protect and restore dopamine (DA) neurons in injury models and is being evaluated for the treatment of Parkinson's disease.… (More)