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spergualin

Known as: Heptanamide, 7-((aminoiminomethyl)amino)-N-(2-((4-((3-aminopropyl)amino)butyl)amino)-1-hydroxy-2-oxoethyl)-3-hydroxy- 
 
National Institutes of Health

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1992
1992
Deoxyspergualin, an analog of spergualin, has been known as a novel immunosuppressive agent with strong immunosuppressive… Expand
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1987
1987
Chemical modifications of the spermidine moiety of an antitumor antibiotic, spergualin (Ia), and the structure-activity… Expand
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1987
1987
Spergualin was isolated from the culture filtrate of Bacillus laterosporus as an antitumour substance. It had a unique structure… Expand
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1987
1987
Optically active 15-deoxyspergualin (II) and 15-deoxy-11-O-methylspergualin (IIa) were synthesized, and their antitumor… Expand
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1986
1986
Spergualin (SGL), a novel antitumor antibiotic, exhibited strong antitumor activity against transplantable leukemias in mice… Expand
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Highly Cited
1985
Highly Cited
1985
Many analogues and derivatives of an antitumor antibiotic, spergualin, were synthesized, and the relationships between the… Expand
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1985
1985
The cytotoxicity of spergualin on cultured L5178Y cells is dependent on the kind of serum contained in culture media. Spergualin… Expand
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1982
1982
The method for chemical modification of spergualin with retention of the configuration at the C-11 has been achieved by the use… Expand
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Highly Cited
1981
Highly Cited
1981
Sir: In testing the activity of culture filtrates to inhibit focus formation of chicken fibroblasts by Rous sarcoma virus, an… Expand
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1981
1981
Sir: During our studies of antitumor antibiotics, spergualin was discovered in culture filtrates of a Bacillus strain… Expand
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