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spergualin

Known as: Heptanamide, 7-((aminoiminomethyl)amino)-N-(2-((4-((3-aminopropyl)amino)butyl)amino)-1-hydroxy-2-oxoethyl)-3-hydroxy- 
National Institutes of Health

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Highly Cited
1990
Highly Cited
1990
Immunotoxins are potent cell-killing agents that may be useful in the treatment of cancer. The early production of neutralizing… 
1988
1988
Stable spergualin analogues were synthesized by substitutions of the alpha-hydroxyglycine residue of spergualin with various… 
1987
1987
Chemical modifications of the spermidine moiety of an antitumor antibiotic, spergualin (Ia), and the structure-activity… 
1987
1987
Optically active 15-deoxyspergualin (II) and 15-deoxy-11-O-methylspergualin (IIa) were synthesized, and their antitumor… 
1986
1986
Spergualin (SGL), a novel antitumor antibiotic, exhibited strong antitumor activity against transplantable leukemias in mice… 
Highly Cited
1985
Highly Cited
1985
Many analogues and derivatives of an antitumor antibiotic, spergualin, were synthesized, and the relationships between the… 
1985
1985
The cytotoxicity of spergualin on cultured L5178Y cells is dependent on the kind of serum contained in culture media. Spergualin… 
Highly Cited
1982
Highly Cited
1982
The method for chemical modification of spergualin with retention of the configuration at the C-11 has been achieved by the use… 
Highly Cited
1981
Highly Cited
1981
Sir: In testing the activity of culture filtrates to inhibit focus formation of chicken fibroblasts by Rous sarcoma virus, an… 
1981
1981
Sir: During our studies of antitumor antibiotics, spergualin was discovered in culture filtrates of a Bacillus strain…