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silybin

Known as: silibin, silibinin, silybinin 
National Institutes of Health

Related topics

Related topics

9 relations
2,3-dehydrosilybin

Broader (5)

Antineoplastic AgentsAntioxidantsFlavonoidsPlant Extracts

Narrower (3)

Hepar-PascHepatosLagosa

Papers overview

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2012
2012
Inhibition of silibinin on migration and adhesion capacity of human highly metastatic breast cancer cell line, MDA-MB-231, by evaluation of β1-integrin and downstream molecules, Cdc42, Raf-1 and…
Metastasis is a property of malignant cancer cells that requires integrins which with their downstream molecules participate in a… 
Highly Cited
2012
Highly Cited
2012
Silibinin Attenuates Sulfur Mustard Analog-Induced Skin Injury by Targeting Multiple Pathways Connecting Oxidative Stress and Inflammation
Chemical warfare agent sulfur mustard (HD) inflicts delayed blistering and incapacitating skin injuries. To identify effective… 
2008
2008
Isosilibinin inhibits advanced human prostate cancer growth in athymic nude mice: Comparison with silymarin and silibinin
Earlier studies have shown the cancer chemopreventive efficacy of silymarin and its semi‐purified constituent silibinin against… 
2007
2007
Quantitation of silibinin, a putative cancer chemopreventive agent derived from milk thistle (Silybum marianum), in human plasma by high-performance liquid chromatography and identification of…
Silibinin has recently received attention as a potential cancer chemopreventive agent because of its antiproliferative and… 
2006
2006
Silibinin inhibits UVB- and epidermal growth factor–induced mitogenic and cell survival signaling involving activator protein-1 and nuclear factor-κB in mouse epidermal JB6 cells
UVB radiation is the major etiologic factor in the development of nonmelanoma skin cancer. In addition to tumor-initiating effect… 
2005
2005
Silibinin inhibits angiogenesis via Flt-1, but not KDR, receptor up-regulation.
Highly Cited
2003
Highly Cited
2003
Dual efficacy of silibinin in protecting or enhancing ultraviolet B radiation-caused apoptosis in HaCaT human immortalized keratinocytes.
An increasing incidence of human skin cancer and other adverse effects of solar ultraviolet (UV) radiation enhance the need for… 
2001
2001
Lethal ingestion of stored Amanita phalloides mushrooms.
We report the first case of a lethal Amanita phalloides intoxication from stored mushrooms. After picking the mushrooms were kept… 
2000
2000
Human hepatocyte--a model for toxicological studies. Functional and biochemical characterization.
Isolated human hepatocytes (HH) are an accepted model for in vitro experiments for testing liver function and xenobiotic… 
Highly Cited
1995
Highly Cited
1995
[The solubility and bioequivalence of silymarin preparations].
Seven silymarin products (pharmacies only), two of them with two batches each, were analysed for their ingredients, in particular… 
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