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silybin

Known as: silibin, silibinin, silybinin 
National Institutes of Health

Related topics

Related topics

9 relations
2,3-dehydrosilybin

Broader (5)

Antineoplastic AgentsAntioxidantsFlavonoidsPlant Extracts

Narrower (3)

Hepar-PascHepatosLagosa

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Colon cancer chemopreventive efficacy of silibinin through perturbation of xenobiotic metabolizing enzymes in experimental rats.
Highly Cited
2011
Highly Cited
2011
Role of E-cadherin in Antimigratory and Antiinvasive Efficacy of Silibinin in Prostate Cancer Cells
The epithelial-to-mesenchymal transition (EMT) in prostate cancer (PCA) cells is considered prerequisite for acquiring migratory… 
Highly Cited
2010
Highly Cited
2010
Silibinin induced autophagic and apoptotic cell death in HT1080 cells through a reactive oxygen species pathway.
Hepatoprotectant silibinin has anticancer and chemo-preventive effects. In this study, silibinin showed significant inhibitory… 
Highly Cited
2008
Highly Cited
2008
Silymarin production by hairy root culture of Silybum marianum (L.) Gaertn
Silymarin production by hairy root culture of Milk thistle (Silybum marianum L. Gaertn) was investigated using Agrobacterium… 
Highly Cited
2003
Highly Cited
2003
Dual efficacy of silibinin in protecting or enhancing ultraviolet B radiation-caused apoptosis in HaCaT human immortalized keratinocytes.
An increasing incidence of human skin cancer and other adverse effects of solar ultraviolet (UV) radiation enhance the need for… 
Highly Cited
2001
Highly Cited
2001
Beneficial effects of silymarin on estrogen‐induced cholestasis in the rat: A study in vivo and in isolated hepatocyte couplets
The effect of silymarin (SIL) on 17α‐ethynylestradiol (EE)‐induced cholestasis was evaluated in rats. EE (5 mg/kg, subcutaneously… 
Highly Cited
1998
Highly Cited
1998
Reduction of cisplatin toxicity in cultured renal tubular cells by the bioflavonoid quercetin
Abstract Quercetin (QC), a polyphenolic compound widely distributed in fruits and vegetables has recently gained interest due to… 
Highly Cited
1995
Highly Cited
1995
[The solubility and bioequivalence of silymarin preparations].
Seven silymarin products (pharmacies only), two of them with two batches each, were analysed for their ingredients, in particular… 
Highly Cited
1986
Highly Cited
1986
Characterization of a transporting system in rat hepatocytes. Studies with competitive and non-competitive inhibitors of phalloidin transport.
Highly Cited
1984
Highly Cited
1984
Pharmacokinetic studies with silymarin in human serum and bile.
Six subjects were given orally 560 mg of silymarin (silibinin 240 mg = 8 Legalon 70 dragees). The serum concentration curves and… 
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