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siguazodan

Known as: 2-cyano-1-methyl-3-(4-(methyl-6-oxo-1,4,5,6-tetrahydropyridazine-3-yl)phenyl)guanidine 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (4)

GuanidinesPhosphodiesterase InhibitorsPyridazinesVasodilator Agents

Narrower (1)

SK&F 94836

Papers overview

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2000
2000
Phosphodiesterase activity in neutrophils from horses with chronic obstructive pulmonary disease.
2000
2000
Effect of type‐selective inhibitors on cyclic nucleotide phosphodiesterase activity and insulin secretion in the clonal insulin secreting cell line BRIN‐BD11
The cyclic nucleotide phosphodiesterases (PDEs) present in an insulin secreting cell line, BRIN–BD11, were characterized using… 
1999
1999
Suppression of anti-CD3-induced interleukin-4 and interleukin-5 release from splenocytes of Mesocestoides corti-infected BALB/c mice by phosphodiesterase 4 inhibitors.
1998
1998
Phosphodiesterase inhibitors suppress alpha2-adrenoceptor-mediated 5-hydroxytryptamine release from tracheae of newborn rabbits.
1996
1996
Membrane‐bound Phosphodiesterases in Rat Myocardium
Isoenzyme‐specific phosphodiesterase (PDE) inhibitors are potential positive inotropic drugs. For evaluating such drugs in… 
1994
1994
Rolipram, but not siguazodan or zaprinast, inhibits the excitatory noncholinergic neurotransmission in guinea-pig bronchi.
Theophylline has been reported to inhibit excitatory noncholinergic but not cholinergic-neurotransmission in guinea-pig bronchi… 
1994
1994
Photoaffinity labelling of cyclic GMP-inhibited phosphodiesterase (PDE III) in human and rat platelets and rat tissues: effects of phosphodiesterase inhibitors.
1993
1993
Effects of rolipram and siguazodan on the human isolated bronchus and their interaction with isoprenaline and sodium nitroprusside
1 The effects of the selective inhibitors of cyclic AMP phosphodiesterase type IV (rolipram) and type III (siguazodan) and their… 
1993
1993
Comparison of the effects of selective inhibitors of phosphodiesterase types III and IV in airway smooth muscle with differing β‐adrenoceptor subtypes
1 The relaxant properties of the type IV adenosine 3′,5′‐cyclic monophosphate phosphodiesterase (cyclic AMP PDE) inhibitor… 
1990
1990
The effects of siguazodan, a selective phosphodiesterase inhibitor, on human platelet function
1 The effects of siguazodan (SK&F 94836) a selective phosphodiesterase (PDE) inhibitor with inotropic and vasodilator activity… 
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