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Pyridazines

Known as: Pyridazines [Chemical/Ingredient] 
National Institutes of Health

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3,4,5-trichloropyridazine3-amino-4-mercapto-6-methylpyridazine4-hydroxymethyl ambrisentanASP5642
In BloodPyridazinoneagonistsantagonists & inhibitors

Papers overview

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Highly Cited
2018
Highly Cited
2018
Asymmetric Cu-Catalyzed 1,4-Dearomatization of Pyridines and Pyridazines without Preactivation of the Heterocycle or Nucleophile.
We show that a chiral copper hydride (CuH) complex catalyzes C-C bond-forming dearomatization of pyridines and pyridazines at… 
2018
2018
Inverse-Electron-Demand Diels-Alder Reactions for the Synthesis of Pyridazines on DNA.
The synthesis of pyridazines on DNA has been developed on the basis of inverse-electron-demand Diels-Alder (IEDDA) reactions of 1… 
Highly Cited
2013
Highly Cited
2013
Radical-based regioselective C-H functionalization of electron-deficient heteroarenes: scope, tunability, and predictability.
Radical addition processes can be ideally suited for the direct functionalization of heteroaromatic bases, yet these processes… 
Review
2012
Review
2012
Some recent approaches of biologically active substituted pyridazine and phthalazine drugs.
  • M. Asif
  • Current medicinal chemistry
  • 2012
  • Corpus ID: 35099203
Nitrogen atom containing heterocyclic compounds, pyridazines, pyridazinones and phthalazines are important structural feature of… 
Highly Cited
2009
Highly Cited
2009
Asymmetric synthesis of Nitrogen heterocycles
PART 1: Asymmetric Synthesis of Nitrogen Heterocycles Containing Only One Heteroatom ASYMMETRIC SYNTHESIS OF THREE- AND FOUR… 
2007
2007
The discovery of 6-[2-(5-chloro-2-{[(2,4-difluorophenyl)methyl]oxy}phenyl)-1-cyclopenten-1-yl]-2-pyridinecarboxylic acid, GW848687X, a potent and selective prostaglandin EP1 receptor antagonist for…
Review
2004
Review
2004
Analytical mass spectrometry of herbicides.
  • W. L. Budde
  • Mass spectrometry reviews
  • 2004
  • Corpus ID: 21114940
Herbicides are chemical substances that are applied to agricultural soils, gardens, lawns, or plants to destroy or to prevent the… 
Highly Cited
2003
Highly Cited
2003
Estrogenic diazenes: heterocyclic non-steroidal estrogens of unusual structure with selectivity for estrogen receptor subtypes.
1997
1997
Synthesis and analgesic effects of 3-substituted 4,6-diarylpyridazine derivatives of the arylpiperazine class.
Highly Cited
1996
Highly Cited
1996
Synthesis and Reactions of Haloazodienes. A New and General Synthesis of Substituted Pyridazines.
The reaction of dihalohydrazones with Hünig's base gives 1-carbethoxy-3-phenyl-4-haloazodienes in-situ, which were found to… 
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