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recombinational repair

Known as: Homologous Recombination Repair, Recombination Repair 
A DNA repair process that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous… 
National Institutes of Health

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Related topics

34 relations
BRCA1 geneBRCA1 protein, humanBRCA1 wt AlleleCell Survival

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double-strand break repair via homologous recombination

Papers overview

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Highly Cited
2005
Highly Cited
2005
Hypersensitivity of Brca1-deficient MEF to the DNA interstrand crosslinking agent mitomycin C is associated with defect in homologous recombination repair and aberrant S-phase arrest
Hypersensitivity of Brca1-deficient cells to interstrand crosslinking (ICL) agents such as cisplatin and mitomycin C (MMC… 
2005
2005
The association of the DNA repair gene XRCC3 Thr241Met polymorphism with susceptibility to colorectal cancer in a Chinese population.
Highly Cited
2004
Highly Cited
2004
ATM is required for the cellular response to thymidine induced replication fork stress.
Genetically distinct checkpoints, activated as a consequence of either DNA replication arrest or ionizing radiation-induced DNA… 
Review
2003
Review
2003
Checkpoint responses to replication stalling: inducing tolerance and preventing mutagenesis.
2003
2003
Caffeine Could Not Efficiently Sensitize Homologous Recombination Repair-Deficient Cells to Ionizing Radiation-Induced Killing
Abstract Wang, H., Wang, X., Iliakis, G. and Wang, Y. Caffeine Could Not Efficiently Sensitize Homologous Recombination Repair… 
Highly Cited
2002
Highly Cited
2002
Cdc2-cyclin B kinase activity links Crb2 and Rqh1-topoisomerase III.
The availability of a sister chromatid, and thus the cell cycle phase in which DNA double-strand breaks (DSBs) occur, influences… 
Highly Cited
2001
Highly Cited
2001
In vitro evidence for homologous recombinational repair in resistance to melphalan.
BACKGROUND The generation of DNA interstrand cross-links is thought to be important in the cytotoxicity of nitrogen mustard… 
Highly Cited
1999
Highly Cited
1999
A requirement for recombinational repair in Saccharomyces cerevisiae is caused by DNA replication defects of mec1 mutants.
To examine the role of the RAD52 recombinational repair pathway in compensating for DNA replication defects in Saccharomyces… 
Highly Cited
1997
Highly Cited
1997
Fludarabine triphosphate inhibits nucleotide excision repair of cisplatin-induced DNA adducts in vitro.
Fludarabine (9-beta-arabinofuranosyl-2-fluoroadenine-5'-monophosphate) is clinically active against chronic lymphocytic leukemia… 
Highly Cited
1972
Highly Cited
1972
Spontaneous and radiation-induced deletion mutations in Escherichia coli strains with different DNA repair capacities.
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