Skip to search formSkip to main contentSkip to account menu

BRCA1 wt Allele

Known as: BRCC1, BRCA1, FANCS 
Human BRCA1 wild-type allele is located within 17q21 and is approximately 81 kb in length. This allele, which encodes breast cancer type 1… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Abstract Mutations within the tumor suppressor BRCA1 cause the majority of hereditary breast and ovarian cancers. The BRCA1… 
2008
2008
Poly(ADP-ribose) polymerase-1 (PARP-1) facilitates DNA single-strand break-base excision repair to maintain genomic stability… 
2005
2005
PURPOSE To obtain and compare the probabilities of finding a mutation in the BRCA1 or BRCA2 genes, the clinical features, and the… 
2001
2001
The breast- and ovarian-specific tumor suppressor protein, BRCA1, has been implicated in regulating the nuclear processes of… 
Highly Cited
2000
Highly Cited
2000
BRCA1, a breast/ovarian cancer susceptibility gene, undergoes mutations in as many as 50% of familial breast tumors. Recent… 
2000
2000
OBJECTIVE The Wilms' tumor (WT1) gene product is consistently detectable in both normal ovarian germinal epithelium and human… 
Highly Cited
1999
Highly Cited
1999
The role of BRCA1 in progression of sporadic breast cancers has to date been equivocal, although preliminary studies on small… 
Highly Cited
1997
Highly Cited
1997
Loss of heterozygosity (LOH) on chromosome 17 is a frequent genetic alteration in breast cancer. To assess whether the location… 
Review
1996
Review
1996
Because studies of breast cancer patients and their relatives provide statistical evidence for involvement of autosomal dominant… 
Highly Cited
1993
Highly Cited
1993
We have analyzed a single multi-affected breast/ovarian cancer pedigree (BOV3) and have shown consistent inheritance of markers…