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BARD1 Pathway

Known as: BRCA1-dependent Ub-ligase activity 
BRCA1 is a breast and ovarian cancer tumor suppressor protein that associates with BARD1 to form a RING/RING heterodimer. The BRCA1/BARD1 RING… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Significance Posttranslational protein modification by ubiquitin (Ub) regulates aspects of biology, including protein turnover… Expand
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2017
2017
Ubiquitin (Ub) signaling is a diverse group of processes controlled by covalent attachment of small protein Ub and polyUb chains… Expand
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Highly Cited
2013
Highly Cited
2013
Ubiquitylation is an essential posttranslational protein modification that is implicated in a diverse array of cellular functions… Expand
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2011
2011
Radiation-induced toxicity limits the delivery of high-dose radiation to head and neck lesions. The aim of this study was to… Expand
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Highly Cited
2010
Highly Cited
2010
Semisynthetic, mechanism-based protein inhibitors of ubiquitin (Ub) and ubiquitin-like modifier (Ubl) activating enzymes (E1s… Expand
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2010
2010
BackgroundPhosphoenolpyruvate carboxylase (PEPC) is a critical enzyme catalyzing the β-carboxylation of phosphoenolpyruvate (PEP… Expand
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2008
2008
BARD1 was first identified as a BRCA1-interacting protein with tumour-suppressor functions. Some association studies suggested… Expand
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1999
1999
The deubiquitinylating enzymes (DUBs), that release free ubiquitin (Ub) from its precursors or ubiquitinylated proteins, are… Expand
Highly Cited
1989
Highly Cited
1989
Heterologous gene expression in yeast can be increased up to several hundred-fold by expressing a foreign gene as a fusion to the… Expand
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1989
1989
Ubiquitin is encoded as a variable, spacerless repeat of the gene terminating with an additional amino acid or as a gene coding… Expand