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BARD1 Pathway

Known as: BRCA1-dependent Ub-ligase activity 
BRCA1 is a breast and ovarian cancer tumor suppressor protein that associates with BARD1 to form a RING/RING heterodimer. The BRCA1/BARD1 RING… 
National Institutes of Health

Papers overview

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2019
2019
Significance Posttranslational protein modification by ubiquitin (Ub) regulates aspects of biology, including protein turnover… 
Highly Cited
2013
Highly Cited
2010
Highly Cited
2010
Semisynthetic, mechanism-based protein inhibitors of ubiquitin (Ub) and ubiquitin-like modifier (Ubl) activating enzymes (E1s… 
2010
2010
BackgroundPhosphoenolpyruvate carboxylase (PEPC) is a critical enzyme catalyzing the β-carboxylation of phosphoenolpyruvate (PEP… 
2008
2008
BARD1 was first identified as a BRCA1-interacting protein with tumour-suppressor functions. Some association studies suggested… 
1999
1999
The deubiquitinylating enzymes (DUBs), that release free ubiquitin (Ub) from its precursors or ubiquitinylated proteins, are… 
Highly Cited
1989
Highly Cited
1989
1989
1989
Ubiquitin is encoded as a variable, spacerless repeat of the gene terminating with an additional amino acid or as a gene coding…