BRCA1 Associated RING Domain 1 Protein

Known as: BARD-1, BRCA1-Associated RING Domain 1, BRCA1 Associated RING Domain Protein 1 
BRCA1-associated RING domain protein 1 (777 aa, ~87 kDa) is encoded by the human BARD1 gene. This protein plays a role in cell cycle progression, DNA… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The breast and ovarian tumor suppressor BRCA1 constitutes a RING heterodimer E3 ligase with BARD1. BRCA1-associated protein 1… (More)
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Highly Cited
2004
Highly Cited
2004
The N-terminus of the BRCA1 protein bears a RING finger domain that functions as an E3 ubiquitin ligase in vitro where it is able… (More)
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Highly Cited
2003
Highly Cited
2003
The breast and ovarian cancer-specific tumor suppressor RING finger protein BRCA1 has been identified as an E3 ubiquitin (Ub… (More)
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Highly Cited
2002
Highly Cited
2002
The RING finger of BRCA1 confers ubiquitin ligase activity that is markedly enhanced when complexed with another RING-containing… (More)
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Highly Cited
2002
Highly Cited
2002
BRCA1 is a tumor suppressor with several important nuclear functions. BRCA1 has no known cytoplasmic functions. We show here that… (More)
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Highly Cited
2002
Highly Cited
2002
Loss of the tumour suppressor BRCA1 results in profound chromosomal instability. The fundamental defect underlying this… (More)
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Highly Cited
2001
Highly Cited
2001
BRCA1-BARD1 constitutes a heterodimeric RING finger complex associated through its N-terminal regions. Here we demonstrate that… (More)
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Highly Cited
2001
Highly Cited
2001
The RING domain of the breast and ovarian cancer tumor suppressor BRCA1 interacts with multiple cognate proteins, including the… (More)
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1998
1998
Germline alterations of BRCA1 result in susceptibility to breast and ovarian cancer. The protein encoded by BRCA1 interacts in… (More)
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1998
1998
BRCA1-associated RING domain (BARD1) was identified as a protein interacting with the breast cancer gene product BRCA1. The… (More)
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