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rasagiline

Known as: (R)-Indan-1-yl-prop-2-ynyl-amine, rasagiline [Chemical/Ingredient], RAS 
National Institutes of Health

Related topics

Related topics

12 relations

Narrower (6)

AGN 1135AzilectN-propargyl-1-aminoindan mesylateTVP 101

Broader (3)

IndansMonoamine Oxidase InhibitorsNeuroprotective Agents
Rasagiline Tartraterasagiline 1 MG Oral Tablet [Azilect]rasagiline mesylate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Rasagiline for the treatment of Parkinson’s disease: an update
Introduction: Rasagiline is a potent, selective, irreversible Monoamine Oxidase-B (MAO-B) inhibitor, developed to prolong the… 
2013
2013
Effects of simvastatin and rosuvastatin on RAS protein, matrix metalloproteinases and NF‐κB in lung cancer and in normal pulmonary tissues
In this study, we have evaluated effects of 24‐hour treatments with simvastatin or rosuvastatin on RAS protein, NF‐κB and MMP… 
Review
2010
Review
2010
Rasagiline, Parkinson neuroprotection, and delayed-start trials
Rasagiline has been studied as a Parkinson disease (PD) neuroprotective agent in 2 major clinical trials, utilizing the delayed… 
Highly Cited
2003
Highly Cited
2003
Anti-apoptotic action of anti-Alzheimer drug, TV3326 [(N-propargyl)-(3R)-aminoindan-5-yl]-ethyl methyl carbamate, a novel cholinesterase-monoamine oxidase inhibitor
Highly Cited
2002
Highly Cited
2002
Early and Late Gene Changes in MPTP Mice Model of Parkinson's Disease Employing cDNA Microarray
Recently, we reported specific brain gene expression changes in the chronic MPTP model in the late stage of degeneration… 
Highly Cited
2001
Highly Cited
2001
Monoamine oxidase-inhibition and MPTP-induced neurotoxicity in the non-human primate: comparison of rasagiline (TVP 1012) with selegiline
Summary. The neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) has been shown to induce parkinsonism in man and non… 
Highly Cited
2001
Highly Cited
2001
Neuroprotective Effects of Novel Cholinesterase Inhibitors Derived from Rasagiline as Potential Anti‐Alzheimer Drugs
Abstract: TV3326, (N‐propargyl‐(3R)‐aminoindan‐5‐yl‐ethyl, methyl carbamate) was prepared in order to combine the neuroprotective… 
Highly Cited
1998
Highly Cited
1998
Effects of N-propargyl-1-(R)aminoindan (rasagiline) in models of motor and cognition disorders.
N-propargyl-1-(R)aminoindan (rasagiline) is a new and selective irreversible MAO-B inhibitor, currently being considered as the… 
Highly Cited
1998
Highly Cited
1998
(R)(+)-N-propargyl-1-aminoindan (rasagiline) and derivatives: highly selective and potent inhibitors of monoamine oxidase B.
(+)-N-Propargyl-1-aminoindan (rasagiline) and a series of derivatives have been synthesized and screened for monoamine oxidase… 
Highly Cited
1996
Highly Cited
1996
Pharmacology and neuroprotective properties of rasagiline.
Rasagiline [R(+)-N-propargyl-1-aminoindane] is a selective irreversible inhibitor of MAO-B which is not metabolised to… 
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