Azilect
National Institutes of Health
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Introduction: Parkinson‟s disease (PD) is characterized by a chronic progressive loss of nigrostriatal dopaminergic neurons that…
IMPORTANCE
Depression, cognitive impairment, and other nonmotor symptoms (NMSs) are common early in Parkinson disease (PD) and…
This is a case report of a 69-year-old female with Parkinson's disease who developed an asymptomatic eruption on her legs…
KEY POINTS Rasagiline, like selegiline, is an irreversible monoamine oxidase type-B (MAO-B) inhibitor It inhibits the breakdown…
Increasing evidence suggests that oxidative stress (OS)-induced pancreatic β-cell impairments is involved in diabetes and…
Novel therapeutic approaches for the treatment of neurodegenerative disorders comprise drug candidates designed specifically to…
We recently reported that propargylamine derivatives such as rasagiline (Azilect) and its S-isomer TVP1022 are neuroprotective…
The therapeutic use of enzyme inhibitors in treatment of neurodegenerative diseases has its origin in the anti Parkinson action…